AffiliationUniv Arizona, Dept Chem & Biochem
MetadataShow full item record
PublisherTAYLOR & FRANCIS INC
CitationBhumasamudram Jagadish, Nathaniel R. Hurley & Eugene A. Mash (2017) Solvent-free nitration of electron-rich arenes, Synthetic Communications, 47:24, 2395-2398, DOI: 10.1080/00397911.2017.1378682
Rights© 2017 Taylor & Francis
Collection InformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at email@example.com.
AbstractNitration of relatively electron-rich arenes does not require an additive or a solvent. For example, reaction on a gram scale of anisole with acetyl nitrate, generated in situ by mixing 100% HNO3 with acetic anhydride, produced 2,4-dinitroanisole in 82% yield after crystallization of the crude product. Results with five additional monosubstituted benzene derivatives possessing highly activated, weakly activated, or weakly deactivated rings are reported. [GRAPHICS] .
Note12 month embargo; published online: 03 October 2017
VersionFinal accepted manuscript
SponsorsStrategic Environmental Research and Development Program [ER-2221]