Affiliation
Univ Arizona, Dept PsycholUniv Arizona, Dept Neurology
Univ Arizona, BIO5
Issue Date
2018
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HindawiCitation
Sevag Kaladchibachi and Fabian Fernandez, “Precision Light for the Treatment of Psychiatric Disorders,” Neural Plasticity, vol. 2018, Article ID 5868570, 16 pages, 2018. https://doi.org/10.1155/2018/5868570.Journal
Neural PlasticityRights
Copyright © 2018 Sevag Kaladchibachi and Fabian Fernandez. This is an open access article distributed under the Creative Commons Attribution License.Collection Information
This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.Abstract
Circadian timekeeping can be reset by brief flashes of light using stimulation protocols thousands of times shorter than those previously assumed to be necessary for traditional phototherapy. These observations point to a future where flexible architectures of nanosecond-, microsecond-, and millisecond-scale light pulses are compiled to reprogram the brain’s internal clock when it has been altered by psychiatric illness or advanced age. In the current review, we present a chronology of seminal experiments that established the synchronizing influence of light on the human circadian system and the efficacy of prolonged bright-light exposure for reducing symptoms associated with seasonal affective disorder. We conclude with a discussion of the different ways that precision flashes could be parlayed during sleep to effect neuroadaptive changes in brain function. This article is a contribution to a special issue on Circadian Rhythms in Regulation of Brain Processes and Role in Psychiatric Disorders curated by editors Shimon Amir, Karen Gamble, Oliver Stork, and Harry Pantazopoulos.Note
Open Access Article. UA Open Access Publishing Fund.ISSN
2090-59041687-5443
Version
Final published versionAdditional Links
https://www.hindawi.com/journals/np/2018/5868570/ae974a485f413a2113503eed53cd6c53
10.1155/2018/5868570
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Except where otherwise noted, this item's license is described as Copyright © 2018 Sevag Kaladchibachi and Fabian Fernandez. This is an open access article distributed under the Creative Commons Attribution License.