1H, 15N and 13C sequence specific backbone assignment of the vanadate inhibited hematopoietic tyrosine phosphatase
Final Accepted Manuscript
AffiliationUniv Arizona, Dept Chem & Biochem
MetadataShow full item record
CitationMachado, L.E.S.F., Page, R. & Peti, W. Biomol NMR Assign (2018) 12: 5. https://doi.org/10.1007/s12104-017-9770-7
JournalBIOMOLECULAR NMR ASSIGNMENTS
Rights© Springer Science+Business Media B.V. 2017
Collection InformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at firstname.lastname@example.org.
AbstractThe sequence-specific backbone assignment of hematopoietic protein tyrosine phosphatase (HePTP; PTPN7) in presence of vanadate has been determined, based on triple-resonance experiments using uniformly [C-13,N-15]-labeled protein. These assignments facilitate further studies of HePTP in the presence of inhibitors to target leukemia and provide further insights into the function of protein tyrosine phosphatases.
Note12 month embargo; published online: 30 August 2017
VersionFinal accepted manuscript
SponsorsAmerican Diabetes Association Pathway to Stop Diabetes Grant [1-14-ACN-31]; Brazil Initiative Brown University grant; NIH [R01GM098482]
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