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dc.contributor.authorAkhoundi, Farhad
dc.contributor.authorQin, Yukun
dc.contributor.authorPeyghambarian, N.
dc.contributor.authorBarton, Jennifer K.
dc.contributor.authorKieu, Khanh
dc.date.accessioned2018-06-12T22:53:06Z
dc.date.available2018-06-12T22:53:06Z
dc.date.issued2018-05
dc.identifier.citationFarhad Akhoundi, Yukun Qin, N. Peyghambarian, Jennifer K. Barton, and Khanh Kieu, "Compact fiber-based multi-photon endoscope working at 1700 nm," Biomed. Opt. Express 9, 2326-2335 (2018)en_US
dc.identifier.issn2156-7085
dc.identifier.issn2156-7085
dc.identifier.pmid29760991
dc.identifier.doi10.1364/BOE.9.002326
dc.identifier.urihttp://hdl.handle.net/10150/627951
dc.description.abstractWe present the design, implementation and performance analysis of a compact multi-photon endoscope based on a piezo electric scanning tube. A miniature objective lens with a long working distance and a high numerical aperture (approximate to 0.5) is designed to provide a diffraction limited spot size. Furthermore, a 1700 nm wavelength femtosecond fiber laser is used as an excitation source to overcome the scattering of biological tissues and reduce water absorption. Therefore, the novel optical system along with the unique wavelength allows us to increase the imaging depth. We demonstrate that the endoscope is capable of performing third and second harmonic generation (THG/SHG) and three-photon excitation fluorescence (3PEF) imaging over a large field of view (> 400 mu m) with high lateral resolution (2.2 mu m). The compact and lightweight probe design makes it suitable for minimally-invasive in-vivo imaging as a potential alternative to surgical biopsies. (C) 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreementen_US
dc.description.sponsorshipNSF ECCS [1610048]; NIH [R01EB020605]; State of Arizona TRIF fundingen_US
dc.language.isoenen_US
dc.publisherOPTICAL SOC AMERen_US
dc.relation.urlhttps://www.osapublishing.org/abstract.cfm?URI=boe-9-5-2326en_US
dc.rights© 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement.en_US
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.titleCompact fiber-based multi-photon endoscope working at 1700 nmen_US
dc.typeArticleen_US
dc.contributor.departmentUniv Arizona, Coll Opt Scien_US
dc.identifier.journalBIOMEDICAL OPTICS EXPRESSen_US
dc.description.noteOpen access journal.en_US
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.en_US
dc.eprint.versionFinal published versionen_US
dc.source.journaltitleBiomedical Optics Express
dc.source.volume9
dc.source.issue5
dc.source.beginpage2326
refterms.dateFOA2018-06-12T22:53:06Z


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