Show simple item record

dc.contributor.authorAngelos, P.
dc.contributor.authorHartl, D.M.
dc.contributor.authorShah, J.P.
dc.contributor.authorNixon, I.J.
dc.contributor.authorOwen, R.P.
dc.contributor.authorRinaldo, A.
dc.contributor.authorRodrigo, J.P.
dc.contributor.authorShaha, A.R.
dc.contributor.authorSilver, C.E.
dc.contributor.authorSuárez, C.
dc.contributor.authorFerlito, A.
dc.date.accessioned2018-06-18T22:23:16Z
dc.date.available2018-06-18T22:23:16Z
dc.date.issued2018-03
dc.identifier.citationP. Angelos, D.M. Hartl, J.P. Shah, I.J. Nixon, R.P. Owen, A. Rinaldo, J.P. Rodrigo, A.R. Shaha, C.E. Silver, C. Suárez, A. Ferlito, Ethical issues in non-intervention trials for thyroid cancer, European Journal of Surgical Oncology, 44 (3), pp 316-320, https://doi.org/10.1016/j.ejso.2017.03.002en_US
dc.identifier.issn07487983
dc.identifier.pmid28343732
dc.identifier.doi10.1016/j.ejso.2017.03.002
dc.identifier.urihttp://hdl.handle.net/10150/627978
dc.description.abstractIn recent years, the increasing numbers of small, apparently indolent thyroid cancers diagnosed in the world have encouraged investigators to consider non-intervention as an alternative to surgical management. In the following pages, the prospect of a non-intervention trial for thyroid cancer is considered with attention to the ethical issues that such a trial might raise. Such a non-intervention trial is analyzed relative to 7 ethical considerations: the social or scientific value of the research, the scientific validity of the trial, the necessity of fair selection of participants, a favorable risk-benefit ratio for trial participants, independent review of the trial, informed consent, and allowing the study participants to withdraw from the trial. A non-intervention trial for thyroid cancer is also considered relative to the central concept of equipoise. (C) 2017 Elsevier Ltd, BASO similar to The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.en_US
dc.language.isoenen_US
dc.publisherELSEVIER SCI LTDen_US
dc.relation.urlhttp://linkinghub.elsevier.com/retrieve/pii/S0748798317303682en_US
dc.rights© 2017 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.en_US
dc.subjectEthicsen_US
dc.subjectThyroid canceren_US
dc.subjectEquipoiseen_US
dc.subjectNon-interventionen_US
dc.subjectResearch ethicsen_US
dc.subjectClinical trialsen_US
dc.titleEthical issues in non-intervention trials for thyroid canceren_US
dc.typeArticleen_US
dc.contributor.departmentUniv Arizona, Coll Meden_US
dc.identifier.journalEJSOen_US
dc.description.note12 month embargo; published online: 16 March 2017en_US
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.en_US
dc.eprint.versionFinal accepted manuscripten_US
dc.source.journaltitleEuropean Journal of Surgical Oncology
dc.source.volume44
dc.source.issue3
dc.source.beginpage316
dc.source.endpage320
refterms.dateFOA2018-03-16T00:00:00Z


Files in this item

Thumbnail
Name:
EJSO-D-16-00666R1.pdf
Size:
523.1Kb
Format:
PDF
Description:
Final Accepted Manuscript

This item appears in the following Collection(s)

Show simple item record