Clinical and Molecular Characteristics and Burden of Kidney Cancer Among Hispanics and Native Americans: Steps Toward Precision Medicine
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Batai_Kidney_cancer_disparitie ...
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Final Accepted Manuscript
Affiliation
Univ Arizona, Dept Surg, Div UrolUniv Arizona, Dept Cellular & Mol Med
Issue Date
2018-06
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CIG MEDIA GROUP, LPCitation
Batai, K., Bergersen, A., Price, E., Hynes, K., Ellis, N. A., & Lee, B. R. (2018). Clinical and Molecular Characteristics and Burden of Kidney Cancer Among Hispanics and Native Americans: Steps Toward Precision Medicine. Clinical genitourinary cancer, 16(3), e535-e541. https://doi.org/10.1016/j.clgc.2018.01.006Journal
CLINICAL GENITOURINARY CANCERRights
© 2018 Elsevier Inc. All rights reserved.Collection Information
This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.Abstract
Cancer disparities in Native Americans (NAs) and Hispanic Americans (HAs) vary significantly in terms of cancer incidence and mortality rates across geographic regions. This review reports that kidney and renal pelvis cancers are unevenly affecting HAs and NAs compared to European Americans of non-Hispanic origin, and that currently there is significant need for improved data and reporting to be able to advance toward genomic-based precision medicine for the assessment of such cancers in these medically underserved populations. More specifically, in states along the US-Mexico border, HAs and NAs have higher kidney cancer incidence rates as well as a higher prevalence of kidney cancer risk factors, including obesity and chronic kidney disease. They are also more likely to receive suboptimal care compared to European Americans. Furthermore, they are underrepresented in epidemiologic, clinical, and molecular genomic studies of kidney cancer. Therefore, we maintain that progress in precision medicine for kidney cancer care requires an understanding of various factors among HAs and NAs, including the real kidney cancer burden, variations in clinical care, issues related to access to care, and specific clinical and molecular characteristics.(C) 2018 Elsevier Inc. All rights reserved.Note
12 month embargo; published online: 12 February 2018ISSN
15587673PubMed ID
29449090Version
Final accepted manuscriptSponsors
American Cancer Society [IRG-16-124-37-IRG]Additional Links
http://linkinghub.elsevier.com/retrieve/pii/S1558767318300338ae974a485f413a2113503eed53cd6c53
10.1016/j.clgc.2018.01.006
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