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    Clinical and Molecular Characteristics and Burden of Kidney Cancer Among Hispanics and Native Americans: Steps Toward Precision Medicine

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    Batai_Kidney_cancer_disparitie ...
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    Description:
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    Author
    Batai, Ken cc
    Bergersen, Andrew
    Price, Elinora
    Hynes, Kieran
    Ellis, Nathan A.
    Lee, Benjamin R.
    Affiliation
    Univ Arizona, Dept Surg, Div Urol
    Univ Arizona, Dept Cellular & Mol Med
    Issue Date
    2018-06
    Keywords
    American Indians
    Cancer health disparities
    Health disparities
    Latinos
    Renal-cell carcinoma
    
    Metadata
    Show full item record
    Publisher
    CIG MEDIA GROUP, LP
    Citation
    Batai, K., Bergersen, A., Price, E., Hynes, K., Ellis, N. A., & Lee, B. R. (2018). Clinical and Molecular Characteristics and Burden of Kidney Cancer Among Hispanics and Native Americans: Steps Toward Precision Medicine. Clinical genitourinary cancer, 16(3), e535-e541. https://doi.org/10.1016/j.clgc.2018.01.006
    Journal
    CLINICAL GENITOURINARY CANCER
    Rights
    © 2018 Elsevier Inc. All rights reserved.
    Collection Information
    This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.
    Abstract
    Cancer disparities in Native Americans (NAs) and Hispanic Americans (HAs) vary significantly in terms of cancer incidence and mortality rates across geographic regions. This review reports that kidney and renal pelvis cancers are unevenly affecting HAs and NAs compared to European Americans of non-Hispanic origin, and that currently there is significant need for improved data and reporting to be able to advance toward genomic-based precision medicine for the assessment of such cancers in these medically underserved populations. More specifically, in states along the US-Mexico border, HAs and NAs have higher kidney cancer incidence rates as well as a higher prevalence of kidney cancer risk factors, including obesity and chronic kidney disease. They are also more likely to receive suboptimal care compared to European Americans. Furthermore, they are underrepresented in epidemiologic, clinical, and molecular genomic studies of kidney cancer. Therefore, we maintain that progress in precision medicine for kidney cancer care requires an understanding of various factors among HAs and NAs, including the real kidney cancer burden, variations in clinical care, issues related to access to care, and specific clinical and molecular characteristics.(C) 2018 Elsevier Inc. All rights reserved.
    Note
    12 month embargo; published online: 12 February 2018
    ISSN
    15587673
    PubMed ID
    29449090
    DOI
    10.1016/j.clgc.2018.01.006
    Version
    Final accepted manuscript
    Sponsors
    American Cancer Society [IRG-16-124-37-IRG]
    Additional Links
    http://linkinghub.elsevier.com/retrieve/pii/S1558767318300338
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.clgc.2018.01.006
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    UA Faculty Publications

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