Behavioral Intervention in Adolescents Improves Bone Mass, Yet Lactose Maldigestion Is a Barrier
Van Loan, Marta
AffiliationUniv Arizona, Dept Nutr Sci
MetadataShow full item record
CitationLee Y, Savaiano DA, McCabe GP, Pottenger FM, Welshimer K, Weaver CM, McCabe LD, Novotny R, Read M, Going S, Mason A, Van Loan M, Boushey CJ. Behavioral Intervention in Adolescents Improves Bone Mass, Yet Lactose Maldigestion Is a Barrier. Nutrients. 2018; 10(4):421.
Rights© 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.
Collection InformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at email@example.com.
AbstractCalcium intake during adolescence is important for attainment of peak bone mass. Lactose maldigestion is an autosomal recessive trait, leading to lower calcium intake. The Adequate Calcium Today study aimed to determine if a school-based targeted behavioral intervention over one year could improve calcium intake and bone mass in early adolescent girls. The school-randomized intervention was conducted at middle schools in six states over one school year. A total of 473 girls aged 10-13 years were recruited for outcome assessments. Bone mineral content (BMC) was determined by dual energy X-ray absorptiometry. Dietary calcium intake was assessed with a semi-quantitative food frequency questionnaire. Baseline calcium intake and BMC were not significantly different between groups. After the intervention period, there were no differences in changes in calcium intake and BMC at any site between groups. An unanticipated outcome was a greater increase in spinal BMC among lactose digesters than lactose maldigesters in the intervention schools only (12 months) (6.9 +/- 0.3 g vs. 6.0 +/- 0.4 g, p = 0.03) and considering the entire study period (18 months) (9.9 +/- 0.4 vs. 8.7 +/- 0.5 g, p < 0.01). Overall, no significant differences between the intervention and control schools were observed. However, lactose digesters who received the intervention program increased bone mass to a greater extent than lactose maldigesters.
VersionFinal published version
SponsorsIFAFS of the USDA Cooperative State Research, Education and Extension Service [00-52102-9696]
- Perceived milk intolerance is related to bone mineral content in 10- to 13-year-old female adolescents.
- Authors: Matlik L, Savaiano D, McCabe G, VanLoan M, Blue CL, Boushey CJ
- Issue date: 2007 Sep
- Lactose intolerance and self-reported milk intolerance: relationship with lactose maldigestion and nutrient intake. Lactase Deficiency Study Group.
- Authors: Carroccio A, Montalto G, Cavera G, Notarbatolo A
- Issue date: 1998 Dec
- Milk, rather than other foods, is associated with vertebral bone mass and circulating IGF-1 in female adolescents.
- Authors: Esterle L, Sabatier JP, Guillon-Metz F, Walrant-Debray O, Guaydier-Souquières G, Jehan F, Garabédian M
- Issue date: 2009 Apr
- Lactose malabsorption, calcium intake, and bone mass in children and adolescents.
- Authors: Medeiros LC, Lederman HM, de Morais MB
- Issue date: 2012 Feb
- Calcium supplementation and bone mineral accretion in Chinese adolescents aged 12-14 years: a 12-month, dose-response, randomised intervention trial.
- Authors: Ma XM, Huang ZW, Yang XG, Su YX
- Issue date: 2014 Nov 14