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dc.contributor.authorLee, Yujin
dc.contributor.authorSavaiano, Dennis
dc.contributor.authorMcCabe, George
dc.contributor.authorPottenger, Francis
dc.contributor.authorWelshimer, Kathleen
dc.contributor.authorWeaver, Connie
dc.contributor.authorMcCabe, Linda
dc.contributor.authorNovotny, Rachel
dc.contributor.authorRead, Marsha
dc.contributor.authorGoing, Scott
dc.contributor.authorMason, April
dc.contributor.authorVan Loan, Marta
dc.contributor.authorBoushey, Carol
dc.date.accessioned2018-08-13T21:29:16Z
dc.date.available2018-08-13T21:29:16Z
dc.date.issued2018-04
dc.identifier.citationLee Y, Savaiano DA, McCabe GP, Pottenger FM, Welshimer K, Weaver CM, McCabe LD, Novotny R, Read M, Going S, Mason A, Van Loan M, Boushey CJ. Behavioral Intervention in Adolescents Improves Bone Mass, Yet Lactose Maldigestion Is a Barrier. Nutrients. 2018; 10(4):421.en_US
dc.identifier.issn2072-6643
dc.identifier.pmid29597337
dc.identifier.doi10.3390/nu10040421
dc.identifier.urihttp://hdl.handle.net/10150/628497
dc.description.abstractCalcium intake during adolescence is important for attainment of peak bone mass. Lactose maldigestion is an autosomal recessive trait, leading to lower calcium intake. The Adequate Calcium Today study aimed to determine if a school-based targeted behavioral intervention over one year could improve calcium intake and bone mass in early adolescent girls. The school-randomized intervention was conducted at middle schools in six states over one school year. A total of 473 girls aged 10-13 years were recruited for outcome assessments. Bone mineral content (BMC) was determined by dual energy X-ray absorptiometry. Dietary calcium intake was assessed with a semi-quantitative food frequency questionnaire. Baseline calcium intake and BMC were not significantly different between groups. After the intervention period, there were no differences in changes in calcium intake and BMC at any site between groups. An unanticipated outcome was a greater increase in spinal BMC among lactose digesters than lactose maldigesters in the intervention schools only (12 months) (6.9 +/- 0.3 g vs. 6.0 +/- 0.4 g, p = 0.03) and considering the entire study period (18 months) (9.9 +/- 0.4 vs. 8.7 +/- 0.5 g, p < 0.01). Overall, no significant differences between the intervention and control schools were observed. However, lactose digesters who received the intervention program increased bone mass to a greater extent than lactose maldigesters.en_US
dc.description.sponsorshipIFAFS of the USDA Cooperative State Research, Education and Extension Service [00-52102-9696]en_US
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.relation.urlhttp://www.mdpi.com/2072-6643/10/4/421en_US
dc.rights© 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.en_US
dc.subjectadolescentsen_US
dc.subjectboneen_US
dc.subjectcalciumen_US
dc.subjectperceived milk intoleranceen_US
dc.subjectlactose maldigestionen_US
dc.titleBehavioral Intervention in Adolescents Improves Bone Mass, Yet Lactose Maldigestion Is a Barrieren_US
dc.typeArticleen_US
dc.contributor.departmentUniv Arizona, Dept Nutr Scien_US
dc.identifier.journalNUTRIENTSen_US
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.en_US
dc.eprint.versionFinal published versionen_US
dc.source.journaltitleNutrients
dc.source.volume10
dc.source.issue4
dc.source.beginpage421
refterms.dateFOA2018-08-13T21:29:16Z


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