A light-fluence-independent method for the quantitative analysis of dynamic contrast-enhanced multispectral optoacoustic tomography (DCE MSOT)
AuthorHupple, Clinton W.
Burton, Neal C.
Pagel, Mark D.
McNally, Lacey R.
AffiliationUniv Arizona, Dept Med Imaging
KeywordsDynamic contrast enhanced imaging
Multispectral optoacoustic tomography
MetadataShow full item record
PublisherELSEVIER GMBH, URBAN & FISCHER VERLAG
CitationHupple, C. W., Morscher, S., Burton, N. C., Pagel, M. D., McNally, L. R., & Cárdenas-Rodríguez, J. (2018). A light-fluence-independent method for the quantitative analysis of dynamic contrast-enhanced multispectral optoacoustic tomography (DCE MSOT). Photoacoustics, 10, 54-64.
Rights© 2018 The Authors. Published by Elsevier GmbH.
Collection InformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at email@example.com.
AbstractMultiSpectral Optoacoustic Tomography (MSOT) is an emerging imaging technology that allows for data acquisition at high spatial and temporal resolution. These imaging characteristics are advantageous for Dynamic Contrast Enhanced (DCE) imaging that can assess the combination of vascular flow and permeability. However, the quantitative analysis of DCE MSOT data has not been possible due to complications caused by wavelength-dependent light attenuation and variability in light fluence at different anatomical locations. In this work we present a new method for the quantitative analysis of DCE MSOT data that is not biased by light fluence. We have named this method the two-compartment linear standard model (2C-LSM) for DCE MSOT. (C) 2018 The Authors. Published by Elsevier GmbH.
NoteOpen access journal.
VersionFinal published version
SponsorsUniversity of Arizona Cancer Center; National Institute of Health [R01CA167183, R01CA169774, P30CA023074]
- Semi-quantitative Multispectral Optoacoustic Tomography (MSOT) for volumetric PK imaging of gastric emptying.
- Authors: Morscher S, Driessen WH, Claussen J, Burton NC
- Issue date: 2014 Sep
- Applying dynamic contrast enhanced MSOT imaging to intratumoral pharmacokinetic modeling.
- Authors: Xiao TG, Weis JA, Gayzik FS, Thomas A, Chiba A, Gurcan MN, Topaloglu U, Samykutty A, McNally LR
- Issue date: 2018 Sep
- Multispectral optoacoustic tomography of the human breast: characterisation of healthy tissue and malignant lesions using a hybrid ultrasound-optoacoustic approach.
- Authors: Becker A, Masthoff M, Claussen J, Ford SJ, Roll W, Burg M, Barth PJ, Heindel W, Schäfers M, Eisenblätter M, Wildgruber M
- Issue date: 2018 Feb
- Dual-Modality Surface-Enhanced Resonance Raman Scattering and Multispectral Optoacoustic Tomography Nanoparticle Approach for Brain Tumor Delineation.
- Authors: Neuschmelting V, Harmsen S, Beziere N, Lockau H, Hsu HT, Huang R, Razansky D, Ntziachristos V, Kircher MF
- Issue date: 2018 Jun
- Towards Quantitative Evaluation of Tissue Absorption Coefficients Using Light Fluence Correction in Optoacoustic Tomography.
- Authors: Brochu FM, Brunker J, Joseph J, Tomaszewski MR, Morscher S, Bohndiek SE
- Issue date: 2017 Jan