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dc.contributor.advisorSbarra, David
dc.contributor.authorCook, Chelsea Claire
dc.creatorCook, Chelsea Claire
dc.date.accessioned2018-10-17T02:41:48Z
dc.date.available2018-10-17T02:41:48Z
dc.date.issued2018
dc.identifier.citationCook, Chelsea Claire. (2018). A PILOT STUDY OF DNA METHYLATION ACROSS THE SEROTONIN TRANSPORTER GENE FOLLOWING MARITAL SEPARATION (Bachelor's thesis, University of Arizona, Tucson, USA).
dc.identifier.urihttp://hdl.handle.net/10150/630411
dc.description.abstractMarital separation and divorce are stressful life transitions associated with increased risk for a range of poor mental and physical health outcomes. A key task for research in this area is to identify individual differences that may shape risk for these adverse outcomes. This report examines the association between DNA methylation across the serotonin transporter gene (SLC6A4) promoter region and self-reported emotional distress in a sample of 47 adults following a recent marital separation. Greater relative hypermethylation in the gene was associated with less subjective separation-related psychological distress. Significantly stronger negative associations were observed between methylation and psychological adjustment among participants who had more recently separated from their former partner. Although results derived from small samples should be considered preliminary, the current study raises a series of new questions about the role of DNA methylation and psychosocial adaptation to stressful life events such as divorce, and future studies can be informed by these findings.
dc.language.isoen
dc.publisherThe University of Arizona.
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.titleA PILOT STUDY OF DNA METHYLATION ACROSS THE SEROTONIN TRANSPORTER GENE FOLLOWING MARITAL SEPARATION
dc.typetext
dc.typeElectronic Thesis
thesis.degree.levelbachelors
thesis.degree.disciplineHonors College
thesis.degree.disciplinePhysiology
thesis.degree.nameB.S.
refterms.dateFOA2018-10-17T02:41:48Z


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