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dc.contributor.advisorWatson, Ronald
dc.contributor.authorDhanoa, Harman
dc.creatorDhanoa, Harman
dc.date.accessioned2018-10-17T02:43:17Z
dc.date.available2018-10-17T02:43:17Z
dc.date.issued2018
dc.identifier.citationDhanoa, Harman. (2018). PROBIOTICS FOR THE MANAGEMENT OF RHEUMATOID ARTHRITIS (Bachelor's thesis, University of Arizona, Tucson, USA).
dc.identifier.urihttp://hdl.handle.net/10150/630439
dc.description.abstractThe human body contains millions of diverse microorganisms that collectively make up the human microbiome. There are variations in the density of bacteria across body sites, and the composition of these microbial species is regulated by several factors including genetics, diet, infectious agents, and other environmental triggers. Pioneering research in this field hypothesized that host-microbe equilibrium is essential for the health of the host and that changes or dysbiosis within the equilibrium are associated with the pathogenesis of several diseases. Recent studies have utilized new sequencing technologies to draw an association between dysbiosis and inflammatory disease. Rheumatoid arthritis (RA) is an inflammatory autoimmune disease in which synovial inflammation causes joint failure. Probiotics have the potential to stabilize the host-microbe equilibrium and decrease the inflammatory process. The available randomized clinical trials (RCTs) show that probiotics can reduce proinflammatory cytokines; however, the clinical effects of probiotics on RA disease activity remain unsettled.
dc.language.isoen
dc.publisherThe University of Arizona.
dc.rightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.titlePROBIOTICS FOR THE MANAGEMENT OF RHEUMATOID ARTHRITIS
dc.typetext
dc.typeElectronic Thesis
thesis.degree.levelbachelors
thesis.degree.disciplineHonors College
thesis.degree.disciplinePublic Health
thesis.degree.nameB.S.
refterms.dateFOA2018-10-17T02:43:17Z


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