Software Implementation of a Combined Fluorescence and Swept Source Optical Coherence Tomography Imaging System

Abstract

This paper serves as a detailed overview of the software developed for the Falloposcope endoscope being developed by the Jennifer Barton Optics Tissue Laboratory. The Falloposcope is designed for a screening procedure for early detection of ovarian cancer in the fallopian tubes. The software controls a charge-coupled device (CCD) camera to perform reflectance and fluorescence imaging, which serves to navigate the endoscope to the fallopian tubes and surveil suspicious tissue regions. It also controls a swept source optical coherence tomography (SS-OCT) imaging system to provide high resolution, cross-sectional tomographic images of these tissue regions. CCD imaging is performed using a Princeton Instruments Pixis 1024B Digital CCD camera system. OCT imaging is performed using a Santec HSL-2100 swept source infrared laser and BPD-200-ST photodetector, as well as an AlazarTech ATS-9462 data acquisition board. Data from these instruments is displayed on a graphic user interface written in C++/CLI. This paper details how each of these imaging systems functions, from hardware control through data processing and visualization, as well as how more challenging programming tasks were completed. The core functionality of each system is complete, but there remain some parameters of the OCT data display which remain to be finalized. The available options, as well as the standard practices within the medical industry around OCT imaging, are discussed.