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    Patterns and predictors of depression treatment among adults with chronic kidney disease and depression in ambulatory care settings in the United States

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    Author
    Vadiei, Nina
    Bhattacharjee, Sandipan
    Affiliation
    Univ Arizona, Coll Pharm, Dept Pharm Practice & Sci
    Issue Date
    2019-02-01
    Keywords
    Adults
    Ambulatory care settings
    Antidepressants
    Chronic kidney disease
    Depression
    
    Metadata
    Show full item record
    Publisher
    SPRINGER
    Citation
    Vadiei, N. & Bhattacharjee, S. Int Urol Nephrol (2019) 51: 303. https://doi.org/10.1007/s11255-018-2034-3
    Journal
    INTERNATIONAL UROLOGY AND NEPHROLOGY
    Rights
    © Springer Nature B.V. 2018.
    Collection Information
    This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.
    Abstract
    One in five adults with chronic kidney disease (CKD) in the United States (US) suffers from depression. Comorbid depression in adults with CKD is associated with higher morbidity and mortality. This study used US national survey data to examine patterns and predictors of depression treatment among adults with non-dialysis-dependent CKD in the US. A retrospective, cross-sectional study was conducted using 2014-2015 National Ambulatory Medical Care Survey (NAMCS) data. The final study sample consisted of visits by 9.02 million adults (unweighted n = 262; age ≥ 18 years) with CKD and depression in the US. Depression treatment was defined as antidepressant use with or without psychotherapy. To identify predictors of depression treatment, multivariable logistic regression analysis was conducted adjusting for predisposing, enabling, and need factors. Approximately half of adults with CKD and depression received depression treatment. Primary care was the main setting of treatment, and the most commonly prescribed antidepressant class was selective serotonin reuptake inhibitors. Adults being seen for treatment of a chronic problem were 3.2 times more likely to receive depression treatment (OR 3.20; 95% CI 1.38-7.21). In addition, there was a 9% higher likelihood of receiving depression treatment for each unit increase in total number of medications (OR 1.09; 95% CI 1.01-1.19). Finally, adults receiving care in the South were 63% less likely to receive depression treatment (OR 0.37; 95% CI 0.15-0.89). Depression treatment was recorded in approximately half of US ambulatory care visits involving adults with CKD and depression from 2014 to 2015. Further research is warranted to determine how to appropriately manage treatment of depression in adults with CKD.
    Note
    12 month embargo; published online: 4 December 2018
    ISSN
    1573-2584
    PubMed ID
    30515735
    DOI
    10.1007/s11255-018-2034-3
    Version
    Final accepted manuscript
    Additional Links
    https://link.springer.com/article/10.1007%2Fs11255-018-2034-3
    ae974a485f413a2113503eed53cd6c53
    10.1007/s11255-018-2034-3
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