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dc.contributor.authorAmato, Katherine R
dc.contributor.authorG Sanders, Jon
dc.contributor.authorSong, Se Jin
dc.contributor.authorNute, Michael
dc.contributor.authorMetcalf, Jessica L
dc.contributor.authorThompson, Luke R
dc.contributor.authorMorton, James T
dc.contributor.authorAmir, Amnon
dc.contributor.authorJ McKenzie, Valerie
dc.contributor.authorHumphrey, Gregory
dc.contributor.authorGogul, Grant
dc.contributor.authorGaffney, James
dc.contributor.authorL Baden, Andrea
dc.contributor.authorA O Britton, Gillian
dc.contributor.authorP Cuozzo, Frank
dc.contributor.authorDi Fiore, Anthony
dc.contributor.authorJ Dominy, Nathaniel
dc.contributor.authorL Goldberg, Tony
dc.contributor.authorGomez, Andres
dc.contributor.authorKowalewski, Martin M
dc.contributor.authorJ Lewis, Rebecca
dc.contributor.authorLink, Andres
dc.contributor.authorL Sauther, Michelle
dc.contributor.authorTecot, Stacey
dc.contributor.authorA White, Bryan
dc.contributor.authorE Nelson, Karen
dc.contributor.authorM Stumpf, Rebecca
dc.contributor.authorKnight, Rob
dc.contributor.authorR Leigh, Steven
dc.date.accessioned2019-04-17T22:26:12Z
dc.date.available2019-04-17T22:26:12Z
dc.date.issued2019-03-01
dc.identifier.citationAmato, K. R., Sanders, J. G., Song, S. J., Nute, M., Metcalf, J. L., Thompson, L. R., ... & Gogul, G. (2019). Evolutionary trends in host physiology outweigh dietary niche in structuring primate gut microbiomes. The ISME journal, 13(3), 576.en_US
dc.identifier.issn1751-7370
dc.identifier.pmid29995839
dc.identifier.doi10.1038/s41396-018-0175-0
dc.identifier.urihttp://hdl.handle.net/10150/632072
dc.description.abstractOver the past decade several studies have reported that the gut microbiomes of mammals with similar dietary niches exhibit similar compositional and functional traits. However, these studies rely heavily on samples from captive individuals and often confound host phylogeny, gut morphology, and diet. To more explicitly test the influence of host dietary niche on the mammalian gut microbiome we use 16S rRNA gene amplicon sequencing and shotgun metagenomics to compare the gut microbiota of 18 species of wild non-human primates classified as either folivores or closely related non-folivores, evenly distributed throughout the primate order and representing a range of gut morphological specializations. While folivory results in some convergent microbial traits, collectively we show that the influence of host phylogeny on both gut microbial composition and function is much stronger than that of host dietary niche. This pattern does not result from differences in host geographic location or actual dietary intake at the time of sampling, but instead appears to result from differences in host physiology. These findings indicate that mammalian gut microbiome plasticity in response to dietary shifts over both the lifespan of an individual host and the evolutionary history of a given host species is constrained by host physiological evolution. Therefore, the gut microbiome cannot be considered separately from host physiology when describing host nutritional strategies and the emergence of host dietary niches.en_US
dc.description.sponsorshipNSF (HOMINID) [0935347]; Earth Microbiome Project (W.M. Keck Foundation) [DT061413]; John Templeton Foundation [44000]en_US
dc.language.isoenen_US
dc.publisherNATURE PUBLISHING GROUPen_US
dc.relation.urlhttps://www.nature.com/articles/s41396-018-0175-0en_US
dc.rights© International Society for Microbial Ecology 2018en_US
dc.titleEvolutionary trends in host physiology outweigh dietary niche in structuring primate gut microbiomesen_US
dc.typeArticleen_US
dc.contributor.departmentUniv Arizona, Sch Anthropolen_US
dc.identifier.journalISME JOURNALen_US
dc.description.note6 month embargo; published online: 11 July 2018en_US
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.en_US
dc.eprint.versionFinal accepted manuscripten_US
dc.source.journaltitleThe ISME journal
refterms.dateFOA2019-01-11T00:00:00Z


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