Out of Center Sleep Testing in Ostensibly Healthy Middle Aged to Older Adults
AffiliationAsthma and Airways Research Center, University of Arizona College of Medicine, Tucson, AZ
Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA Asthma and Airways Research Center, University of Arizona College of Medicine, Tucson, AZ
Department of Sleep and Human Factors Research; Institute of Aerospace Medicine; German Aerospace Center; Cologne, Germany
MetadataShow full item record
PublisherArizona Thoracic Society
CitationQuan SF, Lockyer BJ, Batool-Anwar S, Aeschbach D. Out of center sleep testing in ostensibly healthy middle aged to older adults. Southwest J Pulm Crit Care. 2019;18:87-93.
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AbstractBackground: Out of Center Sleep Testing (OCST) is used increasingly to diagnose obstructive sleep apnea (OSA). However, there are few data using OCST that quantify the amount of intrinsic apneic and hypopneic events among asymptomatic healthy persons, especially those who are elderly. This analysis reports the results of OCST in a small group of ostensibly healthy asymptomatic individuals. Methods: The study population was comprised of ostensibly healthy middle-aged to elderly volunteers for studies of circadian physiology. Before undergoing an OCST, they were found to be free of any chronic medical or psychiatry condition by history, physical and psychologic examination and by a variety of questionnaires and laboratory tests. Results: There were 24 subjects ranging in age from 55-70 years who had an OCST performed. Repeat studies were required in only 3 subjects. Over half the study population was over the age of 60 years (54.2% vs 45.8%); the majority were men (70.8%). The mean apnea hypopnea index (AHI) was 9.2 /hour with no difference between younger and older subjects. However, 11 had an AHI > 5 /hour. Five had an AHI >15 /hour and 2 had an AHI >40 /hour. Those with an AHI <15 /hour had a mean AHI of 4.4 /hour (95% CI:2.8-6.0 /hour). Conclusions: Although OCST has a low failure rate, there is a high prevalence of intrinsic obstructive apnea and hypopnea in ostensibly healthy asymptomatic persons.
NoteOpen access journal
VersionFinal published version
SponsorsNational Institute of Aging AG009975