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    Out of Center Sleep Testing in Ostensibly Healthy Middle Aged to Older Adults

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    Author
    Quan, Stuart F
    Lockyer, Brandon J
    Batool-Anwar, Salma
    Aeschbach, Daniel
    Affiliation
    Asthma and Airways Research Center, University of Arizona College of Medicine, Tucson, AZ
    Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA Asthma and Airways Research Center, University of Arizona College of Medicine, Tucson, AZ
    Department of Sleep and Human Factors Research; Institute of Aerospace Medicine; German Aerospace Center; Cologne, Germany
    Issue Date
    2019-04-19
    Keywords
    obstructive sleep apnea
    Elderly
    Normative
    sleep apnea
    
    Metadata
    Show full item record
    Publisher
    Arizona Thoracic Society
    Citation
    Quan SF, Lockyer BJ, Batool-Anwar S, Aeschbach D. Out of center sleep testing in ostensibly healthy middle aged to older adults. Southwest J Pulm Crit Care. 2019;18:87-93.
    Journal
    Southwest Journal of Pulmonary and Critical Care
    Rights
    © the author(s).
    Collection Information
    This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.
    Abstract
    Background: Out of Center Sleep Testing (OCST) is used increasingly to diagnose obstructive sleep apnea (OSA). However, there are few data using OCST that quantify the amount of intrinsic apneic and hypopneic events among asymptomatic healthy persons, especially those who are elderly. This analysis reports the results of OCST in a small group of ostensibly healthy asymptomatic individuals. Methods: The study population was comprised of ostensibly healthy middle-aged to elderly volunteers for studies of circadian physiology. Before undergoing an OCST, they were found to be free of any chronic medical or psychiatry condition by history, physical and psychologic examination and by a variety of questionnaires and laboratory tests. Results: There were 24 subjects ranging in age from 55-70 years who had an OCST performed. Repeat studies were required in only 3 subjects. Over half the study population was over the age of 60 years (54.2% vs 45.8%); the majority were men (70.8%). The mean apnea hypopnea index (AHI) was 9.2 /hour with no difference between younger and older subjects. However, 11 had an AHI > 5 /hour. Five had an AHI >15 /hour and 2 had an AHI >40 /hour. Those with an AHI <15 /hour had a mean AHI of 4.4 /hour (95% CI:2.8-6.0 /hour). Conclusions: Although OCST has a low failure rate, there is a high prevalence of intrinsic obstructive apnea and hypopnea in ostensibly healthy asymptomatic persons.  
    Note
    Open access journal
    ISSN
    2160-6773
    DOI
    10.13175/swjpcc016-19
    Version
    Final published version
    Sponsors
    National Institute of Aging AG009975
    Additional Links
    http://www.swjpcc.com/sleep/2019/4/19/out-of-center-sleep-testing-in-ostensibly-healthy-middle-age.html
    ae974a485f413a2113503eed53cd6c53
    10.13175/swjpcc016-19
    Scopus Count
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    UA Faculty Publications

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