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    Influence of the Vibralung Acoustical Percussor on pulmonary function and sputum expectoration in individuals with cystic fibrosis

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    Author
    Wheatley, Courtney M
    Baker, Sarah E
    Daines, Cori M
    Phan, Hanna
    Martinez, Marina G
    Morgan, Wayne J
    Snyder, Eric M
    Affiliation
    Univ Arizona, Dept Pharm Practice & Sci
    Univ Arizona, Dept Pharm Practice & Sci
    Univ Arizona, Dept Pediat Pediat Pulmonol & Sleep
    Univ Arizona, USA Dept Pediat Pediat Pulmonol & Sleep
    Univ Arizona, Arizona Clin Res Ctr
    Issue Date
    2018-04-26
    Keywords
    airway clearance therapy
    cystic fibrosis
    diffusing capacity of the lungs for carbon monoxide and nitric oxide
    high-frequency chest wall oscillation/compression
    oscillatory positive expiratory pressure
    pulmonary function
    sputum expectoration/clearance
    
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    Publisher
    SAGE PUBLICATIONS LTD
    Citation
    Wheatley, C. M., Baker, S. E., Daines, C. M., Phan, H., Martinez, M. G., Morgan, W. J., & Snyder, E. M. (2018). Influence of the Vibralung Acoustical Percussor on pulmonary function and sputum expectoration in individuals with cystic fibrosis. Therapeutic Advances in Respiratory Disease. https://doi.org/10.1177/1753466618770997
    Journal
    THERAPEUTIC ADVANCES IN RESPIRATORY DISEASE
    Rights
    © The Author(s), 2018.
    Collection Information
    This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.
    Abstract
    Over two separate studies, 10 and 11 mild to moderate CF patients were recruited for study I and II, respectively. Study I: Vibralung was used for 20 min with either no sound (NS: PEP only) or sound (S: PEP and sound) on randomized visits. Pulmonary function, diffusion capacity of the lungs for carbon monoxide and nitric oxide (DLCO/DLNO), symptoms, and peripheral oxygen saturation (SpO2) were measured at baseline and at 1 and 4 h post treatment. Expectorated sputum was collected over 4 h post treatment. Study II: over 5 days of in-hospital therapy, the Vibralung or vibratory vest therapy (Vest) were used for two therapy sessions per day, with sputum collected for 20 min following each therapy and pulmonary function accessed pre and post each 5-day period (days 1-5 or 7-11) in a randomized crossover design.
    Note
    Open access journal
    ISSN
    1753-4666
    PubMed ID
    29697011
    DOI
    10.1177/1753466618770997
    Version
    Final published version
    Sponsors
    WestMed Inc., Tucson, AZ, USA
    Additional Links
    https://journals.sagepub.com/doi/full/10.1177/1753466618770997
    ae974a485f413a2113503eed53cd6c53
    10.1177/1753466618770997
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