Potential life-years gained over a 5-year period by correcting DOPPS-identified modifiable practices in haemodialysis: results from the European MONITOR-CKD5 study
AffiliationUniv Arizona, Coll Pharm
Univ Arizona, Coll Med
MetadataShow full item record
CitationCombe, C., Mann, J., Goldsmith, D., Dellanna, F., Zaoui, P., London, G., ... & MacDonald, K. (2019). Potential life-years gained over a 5-year period by correcting DOPPS-identified modifiable practices in haemodialysis: results from the European MONITOR-CKD5 study. BMC nephrology, 20(1), 81.
Rights© The Author(s). 2019. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License.
Collection InformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at email@example.com.
AbstractBackgroundDOPPS reported that thousands of life-years could be gained in the US and Europe over 5years by correcting six modifiable haemodialysis practices. We estimated potential life-years gained across 10 European countries using MONITOR-CKD5 study data.MethodsThe DOPPS-based target ranges were used, except for haemoglobin due to label changes, as well as DOPPS-derived relative mortality risks. Percentages of MONITOR-CKD5 patients outside targets were calculated. Consistent with the DOPPS-based analyses, we extrapolated life-years gained for the MONITOR-CKD5 population over 5years if all patients were within targets.ResultsBringing the 10 MONITOR-CKD5 countries' dialysis populations into compliance on the six practices results in a 5-year gain of 97,428 patient-years. In descending order, survival impact was the highest for albumin levels, followed by phosphate levels, vascular access, haemoglobin, dialysis adequacy, and interdialytic weight gain.ConclusionsOptimal management of the six modifiable haemodialysis practices may achieve 6.2% increase in 5-year survival.Trial RegistrationNCT01121237. Clinicaltrials.gov registration May 12, 2010 (retrospectively registered).
NoteOpen access journal
VersionFinal published version
- DOPPS estimates of patient life years attributable to modifiable hemodialysis practices in the United States.
- Authors: Port FK, Pisoni RL, Bragg-Gresham JL, Satayathum SS, Young EW, Wolfe RA, Held PJ
- Issue date: 2004
- Anaemia in haemodialysis patients of five European countries: association with morbidity and mortality in the Dialysis Outcomes and Practice Patterns Study (DOPPS).
- Authors: Locatelli F, Pisoni RL, Combe C, Bommer J, Andreucci VE, Piera L, Greenwood R, Feldman HI, Port FK, Held PJ
- Issue date: 2004 Jan
- Dopps estimate of patient life years attributable to modifiable haemodialysis practices in Belgium.
- Authors: Jadoul M, Lameire N, Bragg-Gresham JL, Eichleay MA, Pisoni RL, Port FK
- Issue date: 2007 Mar-Apr
- Haemodialysis prescription, adherence and nutritional indicators in five European countries: results from the Dialysis Outcomes and Practice Patterns Study (DOPPS).
- Authors: Hecking E, Bragg-Gresham JL, Rayner HC, Pisoni RL, Andreucci VE, Combe C, Greenwood R, McCullough K, Feldman HI, Young EW, Held PJ, Port FK
- Issue date: 2004 Jan
- Dialysis Outcomes and Practice Patterns Study estimate of patient life-years attributable to modifiable haemodialysis practices in Sweden.
- Authors: Wikström B, Jacobson SH, Bragg-Gresham J, Eichleay M, Pisoni R, Port F
- Issue date: 2010 Mar