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dc.contributor.authorSardar, Muhammad
dc.contributor.authorShaikh, Nasreen
dc.contributor.authorMalik, Saad Ullah
dc.contributor.authorFaridi, Warda
dc.contributor.authorBalshan, Eli
dc.contributor.authorManiar, Mihir
dc.date.accessioned2019-06-27T17:11:52Z
dc.date.available2019-06-27T17:11:52Z
dc.date.issued2019-03-05
dc.identifier.citationSardar, M., Shaikh, N., Malik, S. U., Faridi, W., Balshan, E., & Maniar, M. (2019). Progressive left lower extremity weakness in a patient with multiple myeloma: A diagnostic dilemma. SAGE Open Medical Case Reports. https://doi.org/10.1177/2050313X19833506en_US
dc.identifier.issn2050-313X
dc.identifier.pmid30858972
dc.identifier.doi10.1177/2050313X19833506
dc.identifier.urihttp://hdl.handle.net/10150/633049
dc.description.abstractExtramedullary plasmacytoma is a type of plasma cell dyscrasia that can present as solitary tumor or secondary to multiple myeloma. We experienced a case of intramuscular plasmacytoma in the left thigh muscles of a patient secondary to multiple myeloma. A 73-year-old male with relapsed multiple myeloma and bilateral hip arthroplasty complained of lxeft lower limb weakness and hip pain 3 months after relapse. He underwent contrast-enhanced magnetic resonance imaging of lumbar spine and hip which was inconclusive. Subsequently, patient had multiple admissions for progressive lower limb weakness. His clinical course was complicated by a biopsy-proven plasmacytoma of the neck. He received localized radiation therapy to the neck in addition to a change in multiple myeloma chemotherapy regimen, resulting in resolution of the neck mass but his left lower extremity weakness continued to worsen. Repeat magnetic resonance imaging of hip and spine revealed an intramuscular mass in left thigh which was consistent with the diagnosis of extramedullary plasmacytoma on biopsy. Localized radiation to the thigh accompanied with a change in chemotherapy improved his symptoms and a significant reduction in size of plasmacytoma was observed. When an unexplained lower limb weakness is encountered with a history of multiple myeloma, secondary intramuscular plasmacytoma should be considered.en_US
dc.language.isoenen_US
dc.publisherSAGE PUBLICATIONS INCen_US
dc.relation.urlhttps://journals.sagepub.com/doi/10.1177/2050313X19833506en_US
dc.rights© The Author(s) 2019.en_US
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.subjectMultiple myelomaen_US
dc.subjectextramedullary plasmacytomaen_US
dc.subjectleft lower extremity weaknessen_US
dc.subjectmetal artifact reduction protocolen_US
dc.titleProgressive left lower extremity weakness in a patient with multiple myeloma: A diagnostic dilemmaen_US
dc.typeArticleen_US
dc.contributor.departmentUniv Arizona, Dept Meden_US
dc.identifier.journalSAGE OPEN MEDICAL CASE REPORTSen_US
dc.description.noteOpen access journalen_US
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.en_US
dc.eprint.versionFinal published versionen_US
dc.source.journaltitleSAGE open medical case reports
refterms.dateFOA2019-06-27T17:11:52Z


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