The Increased Ratio of Stromal to Epithelial Malignancies in MTF Patients

Abstract

Currently the literature on the risk of breast cancer, comparing MtF patients versus cisgender women, does not show a greater risk for MtF patients. MtF patients are not at a greater risk to develop breast cancer than ciswomen. While the most common type of breast cancer in ciswomen is seen in the epithelial component (12% incidence) of the mammary tissue, herein this specific population, there are case reports (3) of stromal lesions that reflect an increase in the stromal versus epithelial (20 cases reported) ratio of breast malignancies (3:20). The various variables that affect transwomen, like barriers to health or lack of proper education within in the medical community are addressed, in order to conceptualize the current data. The increased ratio of stromal to epithelial malignancies in MtF transgender individuals found in current literature could be attributed to the small smaple size or truly a potential health hazard.