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dc.contributor.advisorPhan, Hanna
dc.contributor.advisorSlack, Marion
dc.contributor.advisorMartin, Jennifer
dc.contributor.authorPark, Haeun
dc.contributor.authorPark, Sohyun
dc.contributor.authorTam, Katie
dc.date.accessioned2019-06-28T21:32:08Z
dc.date.available2019-06-28T21:32:08Z
dc.date.issued2018
dc.identifier.urihttp://hdl.handle.net/10150/633258
dc.descriptionClass of 2018 Abstracten_US
dc.description.abstractSpecific Aims: The aim of this systematic review and meta analysis is to determine the best method to measure medication adherence in cystic fibrosis patients by assessing the rates of adherence to cystic fibrosis medications using different measuring methods. Methods: Using multiple bibliographic databases (including Embase, Pubmed, Cochrane, PsychINFO, WHO, Web of Science, Scopus, and IPS) and reviewing grey literature and association websites, a systematic literature search of articles related to medication adherence in cystic fibrosis patients was conducted in February 2018. The limits applied to all articles were the English language and publication dates between 1989 to the present day. The literature screening was conducted by 3 pharmacy students, professors at the University of Arizona College of Pharmacy, and members of the Cystic Fibrosis Foundation (CFF). The studies were assessed for quality using a abstract and data extraction screening tool. Main Results: The bibliographic database searches generated 1,955 articles, and the grey literature and association websites generated 15 articles. 1,549 of the 1,955 articles and 0 of the 15 articles met the inclusion criteria and underwent data extraction screening. Then, after the abstract screening, 42 articles were identified for eligible to proceed to data extraction. Medication adherence was measured using paper/hard copy reminder tool, pager application, mobile application, electronic device, medication container with tracking, education sessions, and medication organizer. Conclusions: In the preliminary results, seven studies were included in the meta-analysis measuring five different methods of adherence: written diary, electronic monitoring, self-report, Medication Possession Ratio (MPR) and Proportion of Days Covered (PDC). Overall, adherence measured by written diary was significantly different than all other adherence measures except MPR. Further data analysis will be conducted when the data extraction and review is completed by Cystic Fibrosis clinicians and experts.en_US
dc.language.isoen_USen_US
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author.en_US
dc.subjectcystic fibrosisen_US
dc.subjectmedication adherenceen_US
dc.subjectsystematic reviewen_US
dc.subjectmethods of adherenceen_US
dc.subject.meshCystic Fibrosisen_US
dc.subject.meshMedication Adherenceen_US
dc.subject.meshSystematic Reviewen_US
dc.titleSystematic review meta analysis of adherence measures for common chronic medications used in the treatment of cystic fibrosisen_US
dc.typetexten_US
dc.typeElectronic Reporten_US
dc.contributor.departmentCollege of Pharmacy, The University of Arizonaen_US
dc.description.collectioninformationThis item is part of the Pharmacy Student Research Projects collection, made available by the College of Pharmacy and the University Libraries at the University of Arizona. For more information about items in this collection, please contact Jennifer Martin, Associate Librarian and Clinical Instructor, Pharmacy Practice and Science, jenmartin@email.arizona.edu.en_US


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