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dc.contributor.authorGong, Cheng
dc.contributor.authorKulkarni, Nachiket
dc.contributor.authorZhu, Wenbin
dc.contributor.authorNguyen, Christopher David
dc.contributor.authorCuriel-Lewandrowski, Clara
dc.contributor.authorKang, Dongkyun
dc.date.accessioned2019-08-06T17:14:18Z
dc.date.available2019-08-06T17:14:18Z
dc.date.issued2019-06-21
dc.identifier.citationGong, C., Kulkarni, N., Zhu, W., Nguyen, C. D., Curiel-Lewandrowski, C., & Kang, D. (2019). Low-cost, high-speed near infrared reflectance confocal microscope. Biomedical Optics Express, 10(7), 3497-3505.en_US
dc.identifier.issn2156-7085
dc.identifier.doi10.1364/boe.10.003497
dc.identifier.urihttp://hdl.handle.net/10150/633701
dc.description.abstractWe have developed a low-cost, near-infrared (NIR) reflectance confocal microscope (RCM) to overcome challenges in the imaging depth and speed found in our previously-reported smartphone confocal microscope. In the new NIR RCM device, we have used 840 nm superluminescent LED (sLED) to increase the tissue imaging depth and speed. A new confocal detection optics has been developed to maintain high lateral resolution even when a relatively large slit width was used. The material cost of the NIR RCM device was still low, similar to$5,200. The lateral resolution was 1.1 mu m and 1.3 mu m along the vertical and horizontal directions, respectively. Axial resolution was measured as 11.2 mu m. In vivo confocal images of human forearm skin obtained at the imaging speed of 203 frames/sec clearly visualized characteristic epidermal and dermal cellular features of the human skin. (C) 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreementen_US
dc.description.sponsorshipNational Institutes of Health/Fogarty International Center [R21TW010221]en_US
dc.language.isoenen_US
dc.publisherOPTICAL SOC AMERen_US
dc.rightsCopyright © 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreementen_US
dc.titleLow-cost, high-speed near infrared reflectance confocal microscopeen_US
dc.typeArticleen_US
dc.contributor.departmentUniv Arizona, Coll Opt Scien_US
dc.contributor.departmentUniv Arizona, Canc Ctren_US
dc.contributor.departmentUniv Arizona, Dept Biomed Engnen_US
dc.contributor.departmentUniv Arizona, Bio5 Insten_US
dc.identifier.journalBIOMEDICAL OPTICS EXPRESSen_US
dc.description.noteOpen access journalen_US
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.en_US
dc.eprint.versionFinal published versionen_US
dc.source.volume10
dc.source.issue7
dc.source.beginpage3497
refterms.dateFOA2019-08-06T17:14:18Z


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