Pathologic Complete Response After Neoadjuvant Chemoradiation in a Patient with Gastric Neuroendocrine Cancer
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Univ Arizona, Ctr Canc, Radiat OncolUniv Arizona, Ctr Canc, Hematol & Oncol
Issue Date
2019-07-23
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CUREUS INCCitation
Laughlin, Brady & Scott, Aaron & Goyal, Uma. (2019). Pathologic Complete Response After Neoadjuvant Chemoradiation in a Patient with Gastric Neuroendocrine Cancer. Cureus. 10.7759/cureus.5214.Journal
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Copyright © 2019. Laughlin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 3.0.Collection Information
This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.Abstract
Neuroendocrine tumors are about 0.5% of all malignancies. Specifically, for gastrointestinal (GI) malignancies, neuroendocrine tumor incidence is approximately 1%-2% per year. Gastric neuroendocrine neoplasms are rare and consist of various tumor types with differing histomorphology, pathogenesis, and biological behavior. Following surgery, post-operative chemotherapy is generally considered the standard of care. Our case report demonstrates the potential benefit of neoadjuvant concurrent chemoradiotherapy prior to surgery for a malignant gastric neuroendocrine tumor. While radiotherapy has been demonstrated to possibly provide a survival benefit in the treatment of GI neuroendocrine tumors, its use in treatment, particularly neoadjuvantly, needs to be further assessed.Note
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2168-8184Version
Final published versionae974a485f413a2113503eed53cd6c53
10.7759/cureus.5214
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Except where otherwise noted, this item's license is described as Copyright © 2019. Laughlin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 3.0.