A swine model of soy protein–induced food allergenicity: implications in human and swine nutrition
AuthorRadcliffe, John Scott
Brito, Luiz F
Herman, Eliot M
Schinckel, Allan P
AffiliationUniv Arizona, Sch Plant Sci
MetadataShow full item record
PublisherOXFORD UNIV PRESS INC
CitationJohn Scott Radcliffe, Luiz F Brito, Lavanya Reddivari, Monica Schmidt, Eliot M Herman, Allan P Schinckel, A swine model of soy protein–induced food allergenicity: implications in human and swine nutrition, Animal Frontiers, Volume 9, Issue 3, July 2019, Pages 52–59, https://doi.org/10.1093/af/vfz025
RightsCopyright © Radcliffe, Brito, Reddivari, Schmidt, Herman, and Schinckel. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. doi:10.1093/af/vfz025
Collection InformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at firstname.lastname@example.org.
AbstractImplications: Basic digestive processes result in the breakdown of most foodborne antigens; however, a small proportion of food-derived antigens cross the intestinal barrier leading to a brief period of hypersensitivity that is usually followed by the development of oral tolerance. A shift from oral tolerance to sensitization marks the potential for clinical allergy development. The anatomical, physiological, histological, genomic homology, and immunological similarity between pigs and humans make pigs a better model than traditional rodent species to study food allergies and intervention strategies. A subset of pigs naturally develop soy allergies making them an ideal model for soy allergies.
NoteOpen access journal
VersionFinal published version