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dc.contributor.authorMacaraeg, Marci
dc.contributor.authorProytcheva, Maria
dc.contributor.authorKatsanis, Emmanuel
dc.date.accessioned2019-10-08T19:10:13Z
dc.date.available2019-10-08T19:10:13Z
dc.date.issued2019-09-17
dc.identifier.citationMacaraeg M, Proytcheva M, Katsanis E. Transfusion independence after repeated haploidentical hematopoietic cell transplants in a patient with congenital dyserythropoietic anemia type II and hemosiderosis. Pediatr Transplant. 2019;00:e13587. https://doi.org/10.1111/petr.13587en_US
dc.identifier.issn1397-3142
dc.identifier.pmid31529567
dc.identifier.doi10.1111/petr.13587
dc.identifier.urihttp://hdl.handle.net/10150/634692
dc.description.abstractMatched related or unrelated donor allogeneic HCT has occasionally been applied in patients with severe CDA type II and proven to be curative. We report on the first patient with CDA to undergo haploidentical bone marrow transplantation with PT-CY. A 12-year-old boy with severe hemosiderosis, and a, consequently, disturbed BM microenvironment, developed recurrent graft failures and required salvage with two additional haploidentical HCTs. He achieved complete donor chimerism and transfusion independence after the third HCT. Our case underscores the risks associated with performing haploidentical HCT in older pediatric patients with CDA and severe chronic iron overload.en_US
dc.language.isoenen_US
dc.publisherWILEYen_US
dc.rightsCopyright © 2019 Wiley Periodicals, Inc.en_US
dc.subjectcongenital dyserythropoietic anemiasen_US
dc.subjectgraft failureen_US
dc.subjecthaploidentical HCTen_US
dc.titleTransfusion independence after repeated haploidentical hematopoietic cell transplants in a patient with congenital dyserythropoietic anemia type II and hemosiderosisen_US
dc.typeArticleen_US
dc.contributor.departmentUniv Arizona, Dept Pediaten_US
dc.contributor.departmentUniv Arizona, Dept Patholen_US
dc.contributor.departmentUniv Arizona, Dept Meden_US
dc.contributor.departmentUniv Arizona, Dept Immunobiolen_US
dc.identifier.journalPEDIATRIC TRANSPLANTATIONen_US
dc.description.note12 month embargo; published online: 17 September 2019en_US
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.en_US
dc.eprint.versionFinal accepted manuscripten_US


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