• Login
    View Item 
    •   Home
    • UA Faculty Research
    • UA Faculty Publications
    • View Item
    •   Home
    • UA Faculty Research
    • UA Faculty Publications
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of UA Campus RepositoryCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsPublisherJournalThis CollectionTitleAuthorsIssue DateSubmit DateSubjectsPublisherJournal

    My Account

    LoginRegister

    About

    AboutUA Faculty PublicationsUA DissertationsUA Master's ThesesUA Honors ThesesUA PressUA YearbooksUA CatalogsUA Libraries

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Subjective response to intranasal nicotine administration in oral contraceptive users and naturally-cycling women

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    NR_by_OC_Final_clean.pdf
    Size:
    398.5Kb
    Format:
    PDF
    Description:
    Final Accepted Manuscript
    Download
    Author
    Allen, Alicia M.
    Friedrichsen, Samantha C.
    Petersen, Nicole
    Allen, Sharon S.
    Affiliation
    Univ Arizona, Coll Med, Dept Family & Community Med
    Issue Date
    2019-07-03
    Keywords
    Toxicology
    Medicine (miscellaneous)
    Clinical Psychology
    Psychiatry and Mental health
    
    Metadata
    Show full item record
    Publisher
    PERGAMON-ELSEVIER SCIENCE LTD
    Citation
    Allen, A. M., Friedrichsen, S. C., Petersen, N., & Allen, S. S. (2019). Subjective response to intranasal nicotine administration in oral contraceptive users and naturally-cycling women. Addictive behaviors, 98, 106043.
    Journal
    ADDICTIVE BEHAVIORS
    Rights
    Copyright © 2019 Elsevier Ltd. All rights reserved.
    Collection Information
    This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.
    Abstract
    Introduction: Approximately half of premenopausal women who smoke cigarettes also use hormonal contraceptives, with most using oral contraceptives (OCs). While research on the effects of endogenous hormones on smoking-related outcomes continues to expand, little is known about the influence of OCs on similar outcomes. We sought to explore differences in the subjective response to nicotine by OC use after stratifying by testing condition (e.g., smoking status). Methods: Participants were regular (>= 5 cigarettes/day) smokers, classified into OC and naturally cycling (NC) groups. All participants completed four total lab sessions by smoking status (ad libitum smoking, acute smoking abstinence) and anticipated progesterone level (low progesterone week (LPW), high progesterone week (HPW)). Each lab session included self-administration of intranasal nicotine (Time 0 min), assessment of subjective response via the Subjective State Scale (- 30 and + 5 min). Results: Compared to the NC group (n = 28), the OC group (n = 14) was younger (26.2 +/- 1.1 versus 24.2 +/- 1.1; p < 0.001) and had a lower Fagerstriim Test for Nicotine Dependence score (3.4 +/- 0.5 versus 2.6 +/- 0.5; p = 0.011). Progesterone-to-estradiol ratios varied significantly by group at three of the four time points (p < 0.05). During ad libitum smoking, the OC group had significantly lower craving after nicotine administration than the NC group (1.93 +/- 0.33 versus 2.89 +/- 0.23; p = 0.024). No other significant differences in subjective response were identified. Conclusions: Despite significantly different hormone levels, group differences in subjective response to nicotine were relatively few. Additional research is needed to elucidate the mechanisms involved in these observations, as well as explore how they may influence cessation in women.
    Note
    24 month embargo; published online: 3 July 2019
    ISSN
    0306-4603
    DOI
    10.1016/j.addbeh.2019.106043
    Version
    Final accepted manuscript
    Sponsors
    National Institutes of Health (NIH), National Institute on Drug Abuse (NIDA)United States Department of Health & Human ServicesNational Institutes of Health (NIH) - USANIH National Institute on Drug Abuse (NIDA) [R01-DA08075]
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.addbeh.2019.106043
    Scopus Count
    Collections
    UA Faculty Publications

    entitlement

     
    The University of Arizona Libraries | 1510 E. University Blvd. | Tucson, AZ 85721-0055
    Tel 520-621-6442 | repository@u.library.arizona.edu
    DSpace software copyright © 2002-2017  DuraSpace
    Quick Guide | Contact Us | Send Feedback
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.