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dc.contributor.authorVane, Matheus F
dc.contributor.authorCarmona, Maria J C
dc.contributor.authorPereira, Sergio M
dc.contributor.authorKern, Karl B
dc.contributor.authorTimerman, Sérgio
dc.contributor.authorPerez, Guilherme
dc.contributor.authorVane, Luiz Antonio
dc.contributor.authorOtsuki, Denise Aya
dc.contributor.authorAuler, José O C
dc.date.accessioned2019-11-13T21:14:28Z
dc.date.available2019-11-13T21:14:28Z
dc.date.issued2019-10-18
dc.identifier.citationVane, M.F., Carmona, M.J.C., Pereira, S.M. et al. Predictors and their prognostic value for no ROSC and mortality after a non-cardiac surgery intraoperative cardiac arrest: a retrospective cohort study. Sci Rep 9, 14975 (2019) doi:10.1038/s41598-019-51557-3en_US
dc.identifier.issn2045-2322
dc.identifier.pmid31628390
dc.identifier.doi10.1038/s41598-019-51557-3
dc.identifier.urihttp://hdl.handle.net/10150/635526
dc.description.abstractData on predictors of intraoperative cardiac arrest (ICA) outcomes are scarce in the literature. This study analysed predictors of poor outcome and their prognostic value after an ICA. Clinical and laboratory data before and 24 hours (h) after ICA were analysed as predictors for no return of spontaneous circulation (ROSC) and 24 h and 1-year mortality. Receiver operating characteristic curves for each predictor and sensitivity, specificity, positive and negative likelihood ratios, and post-test probability were calculated. A total of 167,574 anaesthetic procedures were performed, including 158 cases of ICAs. Based on the predictors for no ROSC, a threshold of 13 minutes of ICA yielded the highest area under curve (AUC) (0.867[0.80–0.93]), with a sensitivity and specificity of 78.4% [69.6–86.3%] and 89.3% [80.4–96.4%], respectively. For the 1-year mortality, the GCS without the verbal component 24 h after an ICA had the highest AUC (0.616 [0.792–0.956]), with a sensitivity of 79.3% [65.5–93.1%] and specificity of 86.1 [74.4–95.4]. ICA duration and GCS 24 h after the event had the best prognostic value for no ROSC and 1-year mortality. For 24 h mortality, no predictors had prognostic value.en_US
dc.language.isoenen_US
dc.publisherNATURE PUBLISHING GROUPen_US
dc.rightsCopyright © The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License.en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titlePredictors and their prognostic value for no ROSC and mortality after a non-cardiac surgery intraoperative cardiac arrest: a retrospective cohort studyen_US
dc.typeArticleen_US
dc.contributor.departmentUniv Arizona, Saver Heart Ctren_US
dc.identifier.journalSCIENTIFIC REPORTSen_US
dc.description.noteOpen access journalen_US
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.en_US
dc.eprint.versionFinal published versionen_US
dc.source.journaltitleScientific reports
refterms.dateFOA2019-11-13T21:14:29Z


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Copyright © The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License.
Except where otherwise noted, this item's license is described as Copyright © The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License.