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dc.contributor.advisorPatanwala, Asad
dc.contributor.authorKamangar, Kianaz
dc.date.accessioned2019-11-25T20:21:09Z
dc.date.available2019-11-25T20:21:09Z
dc.date.issued2019
dc.identifier.urihttp://hdl.handle.net/10150/636247
dc.descriptionClass of 2019 Abstract, and Posteren_US
dc.description.abstractSpecific Aims: To determine if patients with severe traumatic brain injury receiving a longer-acting neuromuscular blocking agent (rocuronium) in RSI lead to a delay in neurosurgical procedures compared to patients receiving a short-acting neuromuscular blocking agent (succinylcholine). Methods: This was a retrospective cohort study conducted in an academic ED in the United States. A list of patients who received RSI in the ED between the periods 1 Jan 2014 to 1 October 2017, was generated from an RSI database maintained by the department of emergency medicine. Data was collected from electronic medical records and entered into Research Electronic Data Capture (REDCap). The primary outcome variable was the time from RSI to neurosurgical procedure. Information collected included patient demographics, medications used, and clinical information about the head injury. Data regarding timing of RSI, neurosurgeon assessment, and subsequent neurosurgical procedure were also collected. Main Results: The median time from ED presentation to RSI was 18 (10-83) minutes with succinylcholine and 46 (16-133) minutes with rocuronium (p=0.187). The median time from RSI to neurosurgeon assessment was 64 (32-211) minutes with succinylcholine and 123 (34-165) minutes with rocuronium (p=0.950). Neurosurgeon assessment occurred >120 min after RSI in 38% (n=15) patients with succinylcholine and 50% (n=9) patients with rocuronium. The median time from RSI to neurosurgical procedure was 179 (93-390) minutes with succinylcholine and 155 (84-226) minutes with rocuronium (p=0.616). Conclusions: Patients with severe traumatic brain injury receiving rocuronium in RSI did not have a significantly longer time to neurosurgical procedure compared to patients receiving succinylcholine.en_US
dc.language.isoen_USen_US
dc.publisherThe University of Arizona.en_US
dc.rightsCopyright © is held by the author.en_US
dc.subjectRocuroniumen_US
dc.subjectSuccinylcholineen_US
dc.subjectNeurosurgical Proceduresen_US
dc.subjectNeurosurgical Interventionen_US
dc.subjectPatientsen_US
dc.subjectNeuromuscular Blockadeen_US
dc.subjectSevere Traumatic Brain Injuryen_US
dc.subject.meshRocuroniumen_US
dc.subject.meshSuccinylcholineen_US
dc.subject.meshNeurosurgical Proceduresen_US
dc.subject.meshIntracranial Hemorrhage, Hypertensiveen_US
dc.subject.meshPatientsen_US
dc.subject.meshBrain Injuries, Traumaticen_US
dc.subject.meshNeuromuscular Blockadeen_US
dc.titleEffect of Rocuronium Versus Succinylcholine on Time to Neurosurgical Intervention in Patients with Intra-Cranial Hemorrhageen_US
dc.typetexten_US
dc.contributor.departmentCollege of Pharmacy, The University of Arizonaen_US
dc.description.collectioninformationThis item is part of the Pharmacy Student Research Projects collection, made available by the College of Pharmacy and the University Libraries at the University of Arizona. For more information about items in this collection, please contact Jennifer Martin, Associate Librarian and Clinical Instructor, Pharmacy Practice and Science, jenmartin@email.arizona.edu.en_US
refterms.dateFOA2019-11-25T20:21:09Z


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