A Modality-Independent Network Underlies the Retrieval of Large-Scale Spatial Environments in the Human Brain
AffiliationUniv Arizona, Psychol Dept
immersive virtual reality
MetadataShow full item record
CitationHuffman, D. J., & Ekstrom, A. D. (2019). A Modality-Independent Network Underlies the Retrieval of Large-Scale Spatial Environments in the Human Brain. Neuron, 104(3), 611-622.
Rights© 2019 Elsevier Inc.
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AbstractIn humans, the extent to which body-based cues, such as vestibular, somatosensory, and motoric cues, are necessary for normal expression of spatial representations remains unclear. Recent breakthroughs in immersive virtual reality technology allowed us to test how body-based cues influence spatial representations of large-scale environments in humans. Specifically, we manipulated the availability of body-based cues during navigation using an omnidirectional treadmill and a head-mounted display, investigating brain differences in levels of activation (i.e., univariate analysis), patterns of activity (i.e., multivariate pattern analysis), and putative network interactions between spatial retrieval tasks using fMRI. Our behavioral and neuroimaging results support the idea that there is a core, modality-independent network supporting spatial memory retrieval in the human brain. Thus, for well-learned spatial environments, at least in humans, primarily visual input may be sufficient for expression of complex representations of spatial environments.
Note12 month embargo; published online: 6 November 2019
VersionFinal accepted manuscript
SponsorsNational Science Foundation (Behavioral and Cognitive Sciences Division grant)National Science Foundation (NSF) ; National Institutes of Health (National Institute of Neurological Disorders and Stroke grant) [R01NS076856]; National Institutes of Health (National Institute of Mental Health grant) [F32MH116577]
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