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    The effect of CPAP on HRQOL as measured by the Quality of Well-Being Self Administered Questionaire (QWB-SA)

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    Author
    Batool-Anwar, Salma
    Omobomi, Olabimpe
    Quan, Stuart F
    Affiliation
    Univ Arizona, Coll Med
    Univ Arizona, Asthma & Airways Dis Res Ctr
    Issue Date
    2020-01-14
    Keywords
    OSA
    CPAP
    Quality of life
    Quality of well being
    
    Metadata
    Show full item record
    Publisher
    Arizona Thoracic Society
    Citation
    Batool-Anwar S, Omobomi O, Quan SF. The effect of CPAP on HRQOL as Measured by the quality of Well-Being Self-Administered Questionnaire (QWB-SA). Southwest J Pulm Crit Care. 2020;20(1):29-40. doi: https://doi.org/10.13175/swjpcc070-19
    Journal
    Southwest Journal of Pulmonary and Critical Care
    Rights
    Copyright © the author(s).
    Collection Information
    This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.
    Abstract
    Background: To examine the effect of continuous positive airway pressure (CPAP) on Health-related quality of life (HRQoL) as measured by the Quality of Well Being Self-Administered questionnaire (QWB-SA). Methods: Participants from The Apnea Positive Pressure Long-term Efficacy Study (APPLES); a 6-month multicenter randomized, double-blinded intention to treat study, were included in this analysis. The participants with an apnea-hypopnea index >10 events/hour initially randomized to CPAP or Sham group were asked to complete QWB-SA at baseline, 2, 4, and 6-month visits. Results: There were no group differences among either the CPAP or Sham groups. "Mean age was 52±12 [SD] years, AHI 40±25 events/hr, BMI 32±7.1 kg/m2, and Epworth Sleepiness Score (ESS) 10±4 of 24 points." QWB-SA scores were available at baseline, and 2, 4 & 6 months after treatment in CPAP (n 558) and Sham CPAP (n 547) groups. There were no significant differences in QWB scores among mild, moderate or severe OSA participants at baseline. Modest improvement in QWB scores was noted at 2, 4 and 6- months among both Sham and CPAP groups (P <0.05). However, no differences were observed between Sham CPAP and CPAP at any time point. Comparison of the QWB-SA data from the current study with published data in populations with chronic illnesses demonstrated that the impact of OSA is no different than the effect of AIDS and arthritis. Conclusion: Although the QoL measured by the QWB-SA was impaired in OSA it did not have direct proportionality to OSA severity.
    Note
    Open access journal
    DOI
    10.13175/swjpcc070-19
    Version
    Final published version
    Sponsors
    The Apnea Positive Pressure Long-term Efficacy Study (APPLES) study was funded by contract 5UO1-HL-068060 from the National Heart, Lung and Blood Institute. The APPLES pilot studies were supported by grants from the American Academy of Sleep Medicine and the Sleep Medicine Education and Research Foundation to Stanford University and by the National Institute of Neurological Disorders and Stroke (N44-NS-002394) to SAM Technology.
    Additional Links
    http://www.swjpcc.com/sleep/2020/1/14/the-effect-of-cpap-on-hrqol-as-measured-by-the-quality-of-we.html
    ae974a485f413a2113503eed53cd6c53
    10.13175/swjpcc070-19
    Scopus Count
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    UA Faculty Publications

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