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dc.contributor.authorKu, Chung-Hsuan
dc.contributor.authorHuang, Wen-Hung
dc.contributor.authorHsu, Ching-Wei
dc.contributor.authorChen, Yu-Chin
dc.contributor.authorHou, Yi-Chou
dc.contributor.authorWang, I-Kuan
dc.contributor.authorHong, Hsiang-Hsi
dc.contributor.authorWang, Yen-Li
dc.contributor.authorWeng, Cheng-Hao
dc.contributor.authorYen, Tzung-Hai
dc.date.accessioned2020-02-01T01:18:45Z
dc.date.available2020-02-01T01:18:45Z
dc.date.issued2019-11-12
dc.identifier.citationKu, C.-H.; Huang, W.-H.; Hsu, C.-W.; Chen, Y.-C.; Hou, Y.-C.; Wang, I.-K.; Hong, H.-H.; Wang, Y.-L.; Weng, C.-H.; Yen, T.-H. Incidence Rate and Predictors of Globus Pallidus Necrosis after Charcoal Burning Suicide. Int. J. Environ. Res. Public Health 2019, 16, 4426.en_US
dc.identifier.issn1660-4601
dc.identifier.pmid31718107
dc.identifier.doi10.3390/ijerph16224426
dc.identifier.urihttp://hdl.handle.net/10150/636853
dc.description.abstractObjective: This study examined predictors of globus pallidus necrosis as there was a paucity of literature of globus pallidus necrosis resulted from carbon monoxide poisoning after charcoal burning suicide. Methods: A total of 67 patients who had attempted charcoal burning suicide were recruited and stratified into two subgroups based on either presence (n = 40) or absence (n = 27) of globus pallidus necrosis. Demographic, clinical, laboratory, and radiographic data were obtained for cross-sectional analysis. All patients were followed to investigate the risks for mortality. Results: The patients aged 36.8 ± 11.1 years (67.2%) were male. Patients with globus pallidus necrosis were younger (p = 0.044) and had less hypertension (p = 0.015) than patients without globus pallidus necrosis. Furthermore, patients with globus pallidus necrosis suffered from severer medical complications, i.e., fever (p = 0.008), acute myocardial injury (p = 0.022), acute rhabdomyolysis (p = 0.022), and neuropsychiatric symptoms (p < 0.001) than patients without globus pallidus necrosis. Moreover, patients with globus pallidus necrosis received less hyperbaric oxygen therapy than without necrosis (p = 0.024). Two patients (3.0%) died on arrival. In a multivariable regression model, it was revealed that acute myocardial injury (odds ratio 4.6, confidence interval 1.1-18.9, p = 0.034) and neuropsychiatric symptoms (odds ratio 8.0, confidence interval 2.0-31.4, p = 0.003), decreased blood bicarbonate level (odds ratio 0.8, confidence interval 0.7-1.0, p = 0.032), and younger age (odds ratio 0.9, confidence interval 0.9-1.0, p = 0.038) were significant predictors for globus pallidus necrosis. Conclusion: Although patients who had attempted charcoal burning suicide had a low mortality rate (3.0%), globus pallidus necrosis was not uncommon (59.7%) in this population. Further studies are warranted.en_US
dc.description.sponsorshipChang Gung Memorial Hospital, Linkou, TaiwanChang Gung Memorial Hospital [CLRPG3D0016, CORPG5G0051]en_US
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.rightsCopyright © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).en_US
dc.subjectcharcoal burningen_US
dc.subjectglobus pallidus necrosisen_US
dc.subjectmortalityen_US
dc.subjectsuicideen_US
dc.titleIncidence Rate and Predictors of Globus Pallidus Necrosis after Charcoal Burning Suicideen_US
dc.typeArticleen_US
dc.contributor.departmentUniv Arizona, Dept Psycholen_US
dc.identifier.journalINTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTHen_US
dc.description.noteOpen access journalen_US
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.en_US
dc.eprint.versionFinal published versionen_US
dc.source.journaltitleInternational journal of environmental research and public health
refterms.dateFOA2020-02-01T01:18:46Z


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