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dc.contributor.authorWilson, Amanda M
dc.contributor.authorReynolds, Kelly A
dc.contributor.authorJaykus, Lee-Ann
dc.contributor.authorEscudero-Abarca, Blanca
dc.contributor.authorGerba, Charles P
dc.date.accessioned2020-07-06T21:45:34Z
dc.date.available2020-07-06T21:45:34Z
dc.date.issued2019-10-29
dc.identifier.citationWilson, A., Reynolds, K., Jaykus, L., Escudero-Abarca, B., & Gerba, C. (2020). Comparison of estimated norovirus infection risk reductions for a single fomite contact scenario with residual and nonresidual hand sanitizers. American Journal Of Infection Control, 48(5), 538-544. doi: 10.1016/j.ajic.2019.09.010en_US
dc.identifier.issn0196-6553
dc.identifier.pmid31676157
dc.identifier.doi10.1016/j.ajic.2019.09.010
dc.identifier.urihttp://hdl.handle.net/10150/641806
dc.description.abstractBackground: The purpose of this study was to relate experimentally measured log(10) human norovirus reductions for a nonresidual (60% ethanol) and a residual (quaternary ammonium-based) hand sanitizer to infection risk reductions. Methods: Human norovirus log(10) reductions on hands for both sanitizers were experimentally measured using the ASTM International Standard E1838-10 method, with modification. Scenarios included product application to: (1) inoculated fingerpads with 30- and 60-second contact times, and (2) hands followed by inoculation with human norovirus immediately and 4 hours later. Hand sanitizer efficacies were used in a mathematical model estimating norovirus infection risk from a single hand-to-fomite contact under low and high environmental contamination conditions. Results: The largest log(10) reductions for the residual and nonresidual hand sanitizers were for a 60-second contact time, reducing infection risk by approximately 99% and 85%, respectively. Four hours after application, the residual hand sanitizer reduced infection risks by 78.5% under high contamination conditions, whereas the nonresidual hand sanitizer offered no reduction. Discussion: Log(10) virus and infection risk reductions were consistently greater for the residual hand sanitizer under all scenarios. Further data describing residual hand sanitizer efficacy with additional contamination or tactile events are needed. Conclusions: Residual antinoroviral hand sanitizers may reduce infection risks for up to 4 hours. (C) 2019 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.en_US
dc.language.isoenen_US
dc.publisherMOSBY-ELSEVIERen_US
dc.rightsCopyright © 2019 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.en_US
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/
dc.subjectHand sanitizeren_US
dc.subjectNorovirusen_US
dc.subjectrisk reductionen_US
dc.subjectRisk targeten_US
dc.titleComparison of estimated norovirus infection risk reductions for a single fomite contact scenario with residual and nonresidual hand sanitizersen_US
dc.typeArticleen_US
dc.contributor.departmentUniv Arizona, Mel & Enid Zuckerman Coll Publ Hlth, Dept Community Environm & Policyen_US
dc.contributor.departmentUniv Arizona, Coll Agr & Life Sci, Dept Soil Water & Environm Scien_US
dc.identifier.journalAMERICAN JOURNAL OF INFECTION CONTROLen_US
dc.description.note12 month embargo; published online: 29 October 2019en_US
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.en_US
dc.eprint.versionFinal accepted manuscripten_US
dc.source.journaltitleAmerican journal of infection control
dc.source.volume48
dc.source.issue5
dc.source.beginpage538
dc.source.endpage544
dc.source.countryUnited States


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