Nonsteroidal Anti-Inflammatory Drug Use in Chronic Arthritis Pain: Variations by Ethnicity
AuthorVina, Ernest R
Hannon, Michael J
Masood, Hana S
Hausmann, Leslie R M
Ibrahim, Said A
Kwoh, C Kent
AffiliationUniv Arizona, Arthrit Ctr
Univ Arizona, Coll Med, Dept Med, Div Rheumatol
MetadataShow full item record
PublisherELSEVIER SCIENCE INC
CitationVina, E. R., Hannon, M. J., Masood, H. S., Hausmann, L. R., Ibrahim, S. A., Dagnino, J., ... & Kwoh, C. K. (2020). Nonsteroidal Anti-Inflammatory Drug Use in Chronic Arthritis Pain: Variations by Ethnicity. The American journal of medicine, 133(6), 733-740. https://doi.org/10.1016/j.amjmed.2019.11.016
JournalAMERICAN JOURNAL OF MEDICINE
RightsCopyright © 2019 Elsevier Inc. All rights reserved.
Collection InformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at firstname.lastname@example.org.
AbstractPURPOSE: Our objective was to determine if there are ethnic differences in the use of over-the-counter (OTC) and prescription oral nonsteroidal anti-inflammatory drugs (NSAIDs) and if observed ethnic differences persist after adjustment for sociodemographic and clinical factors. METHODS: Knee and hip osteoarthritis study participants were identified. Surveys were administered to collect sociodemographics, clinical information, and oral treatment methods for arthritis. Multivariable logistic regression models were created using a fully conditional method. RESULTS: Hispanics (n = 130), compared to non -Hispanic whites (n = 204), were less likely to have a high school education (26.9% vs 63.2%, P <0.001), less likely to have private medical insurance (P <0.001), and more likely to have worse health (P = 0.004). OTC oral NSAID use was less common (52.9% vs 66.3%, P = 0.019), whereas prescription oral NSAID use was more common (43.4% vs 31.7%, P = 0.042) among Hispanics than non -Hispanic whites in the last 6 months. The ethnic difference in using an OTC NSAID instead of not using any oral NSAID was attenuated and no longer significant when adjusted for age, sex, edu-cation, and medical insurance (odds ratio [OR] 0.54 [95% confidence interval [CI]: 0.28-1.02]). The odds of using a prescription instead of an OTC NSAID remained significantly higher among Hispanics than non -Hispanic whites when adjusted for the same variables (odds ratio 2.17 [95% confidence interval: 1.16-4.05]). CONCLUSIONS: Among patients with osteoarthritis, OTC NSAIDs were less commonly used but prescrip-tion NSAIDs were more commonly used by Hispanics than non -Hispanic whites. Sociodemographic fac-tors partially mediate ethnic differences in the use of oral NSAIDs. (C) 2019 Elsevier Inc. All rights reserved.
Note12 month embargo; published online: 17 December 2019
VersionFinal accepted manuscript
- Demographic, medical, and behavioral characteristics associated with over the counter non-steroidal anti-inflammatory drug use in a population-based cohort: results from the Multi-Ethnic Study of Atherosclerosis.
- Authors: Delaney JA, Biggs ML, Kronmal RA, Psaty BM
- Issue date: 2011 Jan
- Racial/ethnic variations in non-steroidal anti-inflammatory drug (NSAID) use among patients with osteoarthritis.
- Authors: Dominick KL, Bosworth HB, Jeffreys AS, Grambow SC, Oddone EZ, Horner RD
- Issue date: 2004 Oct
- Modifiable Determinants of Exercise Use in a Diverse Ethnic Population With Osteoarthritis.
- Authors: Vina ER, Hannon MJ, Hausmann LRM, Ibrahim SA, Dagnino J, Arellano A, Kwoh CK
- Issue date: 2019 Nov
- Patient-reported communications with pharmacy staff at community pharmacies: the Alabama NSAID Patient Safety Study, 2005-2007.
- Authors: LaCivita C, Funkhouser E, Miller MJ, Ray MN, Saag KG, Kiefe CI, Cobaugh DJ, Allison JJ
- Issue date: 2009 Sep-Oct
- Usage patterns of 'over-the-counter' vs. prescription-strength nonsteroidal anti-inflammatory drugs in France.
- Authors: Duong M, Salvo F, Pariente A, Abouelfath A, Lassalle R, Droz C, Blin P, Moore N
- Issue date: 2014 May