Collapsing glomerulopathy following COVID-19 infection; possible relationship with APOL1 kidney risk alleles in African-Americans

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Author
Mubarak, Muhammed
Tolouian, Ramin
Pezeshgi, Aiyoub
Affiliation
Univ Arizona, Coll Med, Div Nephrol
Issue Date
2020-05-05
Keywords
COVID-19
Acute kidney injury
Collapsing glomerulopathy
Chronic kidney disease
Cytokine storm syndrome
APOL1 kidney risk alleles

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Publisher
NIKAN RESEARCH INST
Citation
Mubarak M, Tolouian R, Pezeshgi A. Collapsing glomerulopathy following COVID-19 infection; possible relationship with APOL1 kidney risk alleles in African-Americans. Immunopathol Persa. 2020;6(2):e18. DOI:10.34172/ipp.2020.18.
Journal
IMMUNOPATHOLOGIA PERSA
Rights
Copyright © 2020 The Author(s); Published by Nickan Research Institute. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0).
Collection Information
This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.
Abstract
Collapsing glomerulopathy (CG) is being increasingly reported in African American patients with COVID-19 infection during the current pandemic. It is possible that CG following COVID-19 infection in this population may be linked to underlying APOL1 kidney risk alleles, which are not uncommon in this ethnic group. This lesion should be considered in the differential diagnosis of rapidly declining renal function in association with heavy proteinuria in the setting of COVID-19 disease, especially in patients of African ancestry.
Note
Open access journal
ISSN
2423-8015
DOI
10.34172/ipp.2020.18
Version
Final published version
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Copyright © 2020 The Author(s); Published by Nickan Research Institute. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0).
Except where otherwise noted, this item's license is described as Copyright © 2020 The Author(s); Published by Nickan Research Institute. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0).