Coronary Angiography and Intervention in Women Resuscitated From Sudden Cardiac Death
Author
May, TeresaSkinner, Kristina
Unger, Barbara
Mooney, Michael
Patel, Nainesh
Dupont, Allison
McPherson, John
McMullan, Paul
Nielsen, Niklas
Seder, David B
Kern, Karl B
Affiliation
Univ Arizona, Sarver Heart CtrIssue Date
2020-03-25
Metadata
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WILEYCitation
May, T., Skinner, K., Unger, B., Mooney, M., Patel, N., Dupont, A., ... & Kern, K. B. (2020). Coronary Angiography and Intervention in Women Resuscitated From Sudden Cardiac Death. Journal of the American Heart Association, 9(7), e015629.Rights
Copyright © 2020 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License.Collection Information
This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.Abstract
BACKGROUND: Coronary artery disease is the primary etiology for sudden cardiac arrest in adults, but potential differences in the incidence and utility of invasive coronary testing between resuscitated men and women have not been extensively evaluated. Our aim was to characterize angiographic similarities and differences between men and women after cardiac arrest. METHODS AND RESULTS: Data from the International Cardiac Arrest Registry-Cardiology database included patients resuscitated from out--of--hospital cardiac arrest of presumed cardiac origin, admitted to 7 academic cardiology/resuscitation centers during 2006 to 2017. Demographics, clinical factors, and angiographic findings of subjects were evaluated in relationship to sex and multivariable logistic regression models created to predict both angiography and outcome. Among 966 subjects, including 277 (29%) women and 689 (71%) men, fewer women had prior coronary artery disease and more had prior congestive heart failure (P=0.05). Women were less likely to have ST--segment-elevation myocardial infarction (32% versus 39%, P=0.04). Among those with ST--segment-elevation myocardial infarctions, identification and distribution of culprit arteries was similar between women and men, and there were no differences in treatment or outcome. In patients without ST--segment elevation post--arrest, women were overall less likely to undergo coronary angiography (51% versus 61%, P<0.02), have a culprit vessel identified (29% versus 45%, P= 0.03), and had fewer culprits acutely occluded (17% versus 28%, P= 0.03). Women were also less often re--vascularized (44% versus 52%, P<0.03). CONCLUSIONS: Among cardiac arrest survivors, women are less likely to undergo angiography or percutaneous coronary intervention than men. Sex disparities for invasive therapies in post--cardiac arrest care need continued attention.Note
Open access journalISSN
2047-9980PubMed ID
32208830Version
Final published versionae974a485f413a2113503eed53cd6c53
10.1161/JAHA.119.015629
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Except where otherwise noted, this item's license is described as Copyright © 2020 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License.
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