Outcomes Associated With Infection of Chronic Pain Spinal Implantable Electronic Devices: Insights From a Nationwide Inpatient Sample Study
Author
Goel, VasudhaKumar, Varun
Agrawal, Shivani N
Patwardhan, Amol M
Ibrahim, Mohab
DeSimone, Daniel C
Sivanesan, Eellan
Banik, Ratan K
Shankar, Hariharan
Affiliation
Univ Arizona, Dept AnesthesiolIssue Date
2020-09-14
Metadata
Show full item recordPublisher
WILEYCitation
Goel, V., Kumar, V., Agrawal, S. N., Patwardhan, A. M., Ibrahim, M., DeSimone, D. C., ... & Shankar, H. (2020). Outcomes Associated With Infection of Chronic Pain Spinal Implantable Electronic Devices: Insights From a Nationwide Inpatient Sample Study. Neuromodulation: Technology at the Neural Interface.Rights
Copyright © 2020 International Neuromodulation Society.Collection Information
This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.Abstract
Objectives Chronic pain spinal implantable electronic devices (CPSIEDs) include devices that provide spinal cord stimulation and intrathecal drug therapy. In this study, we sought to evaluate the trends of CPSIED infections, related complications, and outcomes following the treatment of infection. Materials and Methods The Nationwide Inpatient Sample database contains data from 48 states, and the District of Columbia was used to identify patients with a primary diagnosis of CPSIED infection during the years 2005-2014. Patients with intrathecal pumps for the treatment of spasticity were excluded to limit the study population to patients with chronic pain disorders. Treatments were categorized as: 1) without device removal, 2) pulse generator or pump only removal, 3) intrathecal pump system removal, and 4) spinal cord stimulation system removal. Complications associated with CPSIED infections were identified using administrative billing codes. Results During the study period 2005-2014, a total of 11,041 patients were admitted to the hospital with CPSIED infections. The majority of the patients were treated without surgical intervention (56%), and a smaller proportion underwent complete system explantation (22.7%). In-hospital mortality or permanent disability due to paralysis after CPSIED infection was around 1.83% and 2.77%, respectively. Infectious complications such as meningitis, abscess formation, and osteomyelitis occurred in 4.93%, 5.08%, and 1.5%, respectively. The median cost of hospitalization was around US $14,118.00, and the median length of stay was approximately six days (interquartile range = 4-13 days). Conclusions The complications of CPSIED infection were higher among patients that did not undergo device removal.Note
12 month embargo; first published: 14 September 2020ISSN
1094-7159EISSN
1525-1403PubMed ID
32929856Version
Final accepted manuscriptae974a485f413a2113503eed53cd6c53
10.1111/ner.13263
Scopus Count
Collections
Related articles
- National Perioperative Outcomes for Intrathecal Pump, Spinal Cord Stimulator, and Peripheral Nerve Stimulator Procedures.
- Authors: Abrecht CR, Gabriel RA, Dutton RP, Kaye AD, Michna E, Urman RD
- Issue date: 2015 Nov
- Medical Device Related Pressure Injury in the Treatment of Chronic Pain: An Early Sign of Explantation in Suspected Infection.
- Authors: Sanchis-Lopez N, Romero-Garcia C, De Andres-Ibanez J, Martinez-Plumed R, Rodriguez-Gimillo P, Hernandez-Cadiz MJ, de Medrano VA
- Issue date: 2018 May
- Infectious complications related to intrathecal drug delivery system and spinal cord stimulator system implantations at a comprehensive cancer pain center.
- Authors: Engle MP, Vinh BP, Harun N, Koyyalagunta D
- Issue date: 2013 May-Jun
- Intrathecal Drug Delivery Systems for Cancer Pain Control: Insights on Current Contemporary Practices in the US.
- Authors: Goel V, Kumar V, Blaes A, Gulati A
- Issue date: 2023 Aug
- Infectious Complications of Intrathecal Drug Administration Systems for Spasticity and Chronic Pain: 145 Patients From a Tertiary Care Center.
- Authors: Malheiro L, Gomes A, Barbosa P, Santos L, Sarmento A
- Issue date: 2015 Jul