A Rare Case of Leukemia Cutis as the First Presentation of a Myelodysplastic Syndrome to Acute Myeloid Leukemia Transformation
Name:
1607659144-20201211-29058-myf4 ...
Size:
2.306Mb
Format:
PDF
Description:
Final Published Version
Affiliation
Univ Arizona, Internal Med Hematol & OncolIssue Date
2020-06-19Keywords
leukemia cutistherapy-related myelodysplastic syndrome
acute myeloid leukemia (aml)
new insights
cytogenetic analysis
Metadata
Show full item recordPublisher
CUREUS INCCitation
Findakly, D., & Amar, S. (2020). A Rare Case of Leukemia Cutis as the First Presentation of a Myelodysplastic Syndrome to Acute Myeloid Leukemia Transformation. Cureus, 12(6).Journal
CUREUSRights
Copyright © 2020, Findakly et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Collection Information
This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.Abstract
Leukemia cutis (LC) is a rare presentation of leukemia. It is characterized by the infiltration of leukemic cells into the different layers of the skin causing varying skin manifestations. It can occur before the hematological presentation of leukemia or during the disease course and carries a poor prognosis. Here, we report a patient with therapy-related myelodysplastic syndrome (t-MDS) whose transformation to acute leukemia was heralded by the development of LC. Worrisome cutaneous lesions should not be overlooked, and a skin biopsy should be pursued to confirm the diagnosis. A high index of suspicion is the key to early recognition of sometimes nonspecific skin findings of widespread systemic disease.Note
Open access journalISSN
2168-8184PubMed ID
32577334Version
Final published versionae974a485f413a2113503eed53cd6c53
10.7759/cureus.8698
Scopus Count
Collections
Except where otherwise noted, this item's license is described as Copyright © 2020, Findakly et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Related articles
- Aleukemic Myeloid Leukemia Cutis with a Kikuchi Disease-Like Inflammatory Pattern in Myelodysplastic Syndrome.
- Authors: Khieu M, Beauvais A, Matz R, Bersabe A, Brown P, Brown A, Fillman E, Hall J
- Issue date: 2017 Apr
- Leukemia cutis. Analysis of 50 biopsy-proven cases with an emphasis on occurrence in myelodysplastic syndromes.
- Authors: Longacre TA, Smoller BR
- Issue date: 1993 Sep
- Myeloid leukemia cutis in the setting of myelodysplastic syndrome: a crucial dermatological diagnosis.
- Authors: Patel LM, Maghari A, Schwartz RA, Kapila R, Morgan AJ, Lambert WC
- Issue date: 2012 Apr
- Leukemia Cutis
- Authors: Parsi M, Go MS, Ahmed A
- Issue date: 2020 Jan
- Cutaneous leukaemic infiltrations in a patient with previously undiagnosed myelodysplastic syndrome.
- Authors: Schneider LA, Weber L, Viardot A, Schubert R, Hinrichs R, Scharffetter-Kochanek K
- Issue date: 2004 Sep