Up to 206 Million People Reached and Over 5.4 Million Trained in Cardiopulmonary Resuscitation Worldwide: The 2019 International Liaison Committee on Resuscitation World Restart a Heart Initiative
AuthorBöttiger, Bernd W
Chakra Rao, Ssc
De Caen, Allan
Kern, Karl B
Khan, Abdul Majeed S
Lim, Swee H
Nakagawa, Naomi V
Neumar, Robert W
Nolan, Jerry P
van Grootven, Heleen
Perkins, Gavin D
AffiliationUniv Arizona, Dept Med, Div Cardiol
Keywords“World Restart a Heart”
International Liaison Committee on Resuscitation
MetadataShow full item record
CitationBöttiger, B. W., Lockey, A., Aickin, R., Carmona, M., Cassan, P., Castrén, M., ... & Perkins, G. D. (2020). Up to 206 million people reached and over 5.4 million trained in cardiopulmonary resuscitation worldwide: the 2019 international liaison committee on resuscitation World restart a heart initiative. Journal of the American Heart Association, 9(15), e017230.
Rights© 2020 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
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AbstractSudden out-of-hospital cardiac arrest is the third leading cause of death in industrialized nations. Many of these lives could be saved if bystander cardiopulmonary resuscitation rates were better. "All citizens of the world can save a life-CHECK-CALL-COMPRESS." With these words, the International Liaison Committee on Resuscitation launched the 2019 global "World Restart a Heart" initiative to increase public awareness and improve the rates of bystander cardiopulmonary resuscitation and overall survival for millions of victims of cardiac arrest globally. All participating organizations were asked to train and to report the numbers of people trained and reached. Overall, social media impact and awareness reached up to 206 million people, and >5.4 million people were trained in cardiopulmonary resuscitation worldwide in 2019. Tool kits and information packs were circulated to 194 countries worldwide. Our simple and unified global message, "CHECK-CALL-COMPRESS," will save hundreds of thousands of lives worldwide and will further enable many policy makers around the world to take immediate and sustainable action in this most important healthcare issue and initiative.
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Except where otherwise noted, this item's license is described as © 2020 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
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A NOVEL RESUSCITATION ALGORITHM USING WAVEFORM ANALYSIS AND END-TIDAL CARBON DIOXIDE PRESSURE FOR VENTRICULAR FIBRILLATIONIndik, Julia H; Chaudhry, Fahd Abdullah; Utzinger, Urs; Konhilas, John; Hilwig, Ronald W (The University of Arizona., 2011)Ventricular fibrillation (VF) is a lethal heart rhythm that leads to cardiac arrest. It has been shown that amplitude spectral area (AMSA) in prolonged VF correlates with success of resuscitation. This study will compare traditional resuscitation with a novel resuscitation algorithm using AMSA and end-tidal carbon dioxide (ETCO2) to time defibrillations.VF will be induced in 60 swine. Resuscitation will commence after 10 minutes of untreated VF. Cases will receive defibrillation if AMSA is >19.8 mVHz and ETCO2 >20 mm of Hg, otherwise chest compressions will continue for another 90 seconds. Controls will have standard resuscitation. Sub group analysis will include effect of induced myocardial infarction (MI).End points will include survival, neurologic scores, duration of resuscitation efforts, and number of defibrillations.This experiment will establish whether using AMSA and ETCO2 to time defibrillations results in superior resuscitation compared with standard techniques.
Characterizing the Potential for Neutrophils to Mediate the Inflammation Response Associated with Cardiac Arrest and ResuscitationMcDonagh, Paul; Torrecillas, Vanessa Faith (The University of Arizona., 2013)Post-Resuscitation Injury (PRI) may contribute to poor recovery after cardiac arrest and resuscitation, and this complication may be due to a dramatic inflammatory response suspected to occur in the early hours following successful resuscitation. The purpose of this study was to evaluate whether blood neutrophils, a known source of oxidants under other acute inflammatory conditions, mediate an inflammatory response soon after resuscitation. Using a laboratory model of cardiac arrest and resuscitation (A/R), adult Sprague Dawley rats were anesthetized and subjected to a cardiac arrest and resuscitation protocol. During the experiments, blood samples were taken at specific time points to monitor blood glucose and mean arterial blood pressure. Sham experiments were performed as a control. Tissues from animals receiving no surgical procedures were also obtained as a further control. After two hours of resuscitation, heart, lung, liver, and brain tissues were collected and quick-frozen. Later, samples were thawed, homogenized, and analyzed for neutrophilspecific myeloperoxidase (MPO) accumulation using the Hycult Biotech ELISA kit. MPO accumulation is used as an indicator of neutrophil sequestration in the organ. We found a marked increase in tissue MPO in the lung, indicative of neutrophil accumulation. There was a statistically significant difference (t-Test) between sham vs. resuscitation groups for both hepatic and cardiac tissues. These findings indicate that neutrophils do sequester in the heart and liver in the early hours following successful resuscitation. Because of their potential for oxidative injury, neutrophils likely contribute to the inflammatory response and cardiac stunning observed in the early hours of resuscitation. Efforts to limit neutrophil-mediated microvascular and oxidative injury may reduce PRI and improve recovery.
Mechanical chest compressions for cardiac arrest in the cath-lab: when is it enough and who should go to extracorporeal cardio pulmonary resuscitation?Madsen Hardig, Bjarne; Kern, Karl B; Wagner, Henrik; Univ Arizona, Sarver Heart Ctr (BMC, 2019-06-03)Background Treating patients in cardiac arrest (CA) with mechanical chest compressions (MCC) during percutaneous coronary intervention (PCI) is now routine in many coronary catheterization laboratories (cath-lab) and more aggressive treatment modalities, including extracorporeal CPR are becoming more common. The cath-lab setting enables monitoring of vital physiological parameters and other clinical factors that can potentially guide the resuscitation effort. This retrospective analysis attempts to identify such factors associated with ROSC and survival. Methods In thirty-five patients of which background data, drugs used during the resuscitation and the intervention, PCI result, post ROSC-treatment and physiologic data collected during CPR were compared for prediction of ROSC and survival. Results Eighteen (51%) patients obtained ROSC and 9 (26%) patients survived with good neurological outcome. There was no difference between groups in regards of background data. Patients arriving in the cath-lab with ongoing resuscitation efforts had lower ROSC rate (22% vs 53%; p=0.086) and no survivors (0% vs 50%, p=0.001). CPR time also differentiated resuscitation outcomes (ROSC: 18min vs No ROSC: 50min; p=0.007 and Survivors: 10min vs No Survivors: 45min; p=0.001). Higher arterial diastolic blood pressure was associated with ROSC: 30mmHg vs No ROSC: 19mmHg; p=0.012).Conclusion Aortic diastolic pressure during CPR is the most predictive physiological parameter of resuscitation success. Ongoing CPR upon arrival at the cath-lab and continued MCC beyond 10-20min in the cath-lab were both predictive of poor outcomes. These factors can potentially guide decisions regarding escalation and termination of resuscitation efforts.