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    Radiation dosimetry of a clinical prototype dedicated cone‐beam breast CT system with offset detector

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    Truncated_Detector_DgN_Rev1.pdf
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    Description:
    Final Accepted Manuscript
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    Author
    Tseng, Hsin Wu
    Karellas, Andrew
    Vedantham, Srinivasan
    Affiliation
    Department of Medical Imaging, The University of Arizona
    Department of Biomedical Engineering, The University of Arizona
    Issue Date
    2021-01-26
    Keywords
    breast cancer
    breast CT
    mean glandular dose
    Monte Carlo
    offset detector
    radiation dose
    truncated detector
    
    Metadata
    Show full item record
    Publisher
    John Wiley and Sons Ltd
    Citation
    Tseng, H. W., Karellas, A., & Vedantham, S. (2021). Radiation dosimetry of a clinical prototype dedicated cone‐beam breast CT system with offset detector. Medical Physics.
    Journal
    Medical Physics
    Rights
    © 2021 American Association of Physicists in Medicine.
    Collection Information
    This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.
    Abstract
    Purpose: A clinical-prototype, dedicated, cone-beam breast computed tomography (CBBCT) system with offset detector is undergoing clinical evaluation at our institution. This study is to estimate the normalized glandular dose coefficients ((Formula presented.)) that provide air kerma-to-mean glandular dose conversion factors using Monte Carlo simulations. Materials and methods: The clinical prototype CBBCT system uses 49 kV x-ray spectrum with 1.39 mm 1st half-value layer thickness. Monte Carlo simulations (GATE, version 8) were performed with semi-ellipsoidal, homogeneous breasts of various fibroglandular weight fractions ((Formula presented.), chest wall diameters ((Formula presented.) cm), and chest wall to nipple length ((Formula presented.)), aligned with the axis of rotation (AOR) located at 65 cm from the focal spot to determine the (Formula presented.). Three geometries were considered – (Formula presented.) -cm detector with no offset that served as reference and corresponds to a clinical CBBCT system, (Formula presented.) -cm detector with 5 cm offset, and a (Formula presented.) -cm detector with 10 cm offset. Results: For 5 cm lateral offset, the (Formula presented.) ranged (Formula presented.) mGy/mGy and reduction in (Formula presented.) with respect to reference geometry was observed only for 18 cm ((Formula presented.)) and 20 cm ((Formula presented.)) diameter breasts. For the 10 cm lateral offset, the (Formula presented.) ranged (Formula presented.) mGy/mGy and reduction in (Formula presented.) was observed for all breast diameters. The reduction in (Formula presented.) was (Formula presented.), (Formula presented.), (Formula presented.), (Formula presented.), and (Formula presented.) for 8, 10, 14, 18, and 20 cm diameter breasts, respectively. For a given breast diameter, the reduction in (Formula presented.) with offset-detector geometries was not dependent on (Formula presented.). Numerical fits of (Formula presented.) were generated for each geometry. Conclusion: The (Formula presented.) and the numerical fit, (Formula presented.) would be of benefit for current CBBCT systems using the reference geometry and for future generations using offset-detector geometry. There exists a potential for radiation dose reduction with offset-detector geometry, provided the same technique factors as the reference geometry are used, and the image quality is clinically acceptable. © 2021 American Association of Physicists in Medicine
    Note
    12 month embargo; published 26 January 2021
    ISSN
    0094-2405
    EISSN
    2473-4209
    DOI
    10.1002/mp.14688
    Version
    Final accepted manuscript
    Sponsors
    National Institutes of Health
    ae974a485f413a2113503eed53cd6c53
    10.1002/mp.14688
    Scopus Count
    Collections
    UA Faculty Publications

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