Preliminary Clinical Evaluation of Intrafraction Prostate Displacements for Two Immobilization Systems
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1612430733-1612430729-20210204 ...
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Univ Arizona, Radiat OncolUniv Arizona, Banner Univ Med Ctr, Radiat Oncol Med Phys
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2020-09
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CUREUS INCCitation
Mostafaei, F., Dougherty, S. T., & Hamilton, R. J. (2020). Preliminary Clinical Evaluation of Intrafraction Prostate Displacements for Two Immobilization Systems. Cureus, 12(9).Journal
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© Copyright 2020 Mostafaei et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0.Collection Information
This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.Abstract
Immobilization systems and their corresponding set-up errors influence the clinical target volume to the planning target volume (CTV-PTV) margins, which is critical for hypofractionated prostate stereotactic body radiotherapy (SBRT). This preliminary study evaluates intrafraction prostate displacement for two immobilization systems (A and B). Six consecutive patients having localized prostate cancer and implanted prostate marker seeds were studied. Planar X-ray images were acquired pre- and post-treatment to find the intrafraction prostate displacement. The average absolute displacements (lateral, longitudinal, vertical) were 0.9 +/- 0.4 mm, 1.7 +/- 0.1 mm, 1.3 +/- 0.3 mm (system A), and 0.5 +/- 0.2 ram, 0.6 +/- 0.1 mm, 0.8 +/- 0.3 mm (system B), with average three-dimensional displacements of 2.6 +/- 0.2 mm (system A) and 1.3 +/- 0.2 mm (system B). The computed CTV-PTV margins (lateral, longitudinal, vertical) were 2.5 mm, 2.5 mm, 3.6 mm and 1.4 mm, 1.6 mm, 2.4 mm for systems A and B, respectively. This suggests that the immobilization system influences intrafraction prostate displacement and, therefore, the margins applied. However, the margins found for both systems are comparable to the margins used for hypofractionated prostate SBRT.Note
Open access journalISSN
2168-8184EISSN
2168-8184Version
Final published versionae974a485f413a2113503eed53cd6c53
10.7759/cureus.10206
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Except where otherwise noted, this item's license is described as © Copyright 2020 Mostafaei et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0.