Show simple item record

dc.contributor.authorGilman, Kristy E
dc.contributor.authorLimesand, Kirsten H
dc.date.accessioned2021-04-08T02:06:16Z
dc.date.available2021-04-08T02:06:16Z
dc.date.issued2020-12-09
dc.identifier.citationGilman, K. E., & Limesand, K. H. (2020). The complex role of Prostaglandin E2-EP receptor signaling in wound healing. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology.en_US
dc.identifier.issn1522-1490
dc.identifier.pmid33296281
dc.identifier.doi10.1152/ajpregu.00185.2020
dc.identifier.urihttp://hdl.handle.net/10150/657646
dc.description.abstractProstaglandins are critical lipid mediators involved in the wound healing response, with prostaglandin E2 (PGE2) being the most complex and exhibiting the most diverse physiological outputs. PGE2 signals via four G protein-coupled receptors, termed EP-receptors 1-4 that induce distinct signaling pathways upon activation and lead to an array of different outputs. Recent studies examining the role of PGE2 and EP receptor signaling in wound healing following various forms of tissue damage are discussed in this review.en_US
dc.language.isoenen_US
dc.publisherAmerican Physiological Societyen_US
dc.rightsCopyright © 2021 the American Physiological Societyen_US
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en_US
dc.subjectcell signalingen_US
dc.subjectProstaglandinsen_US
dc.subjectrepairen_US
dc.subjecttissue damageen_US
dc.subjectwound healingen_US
dc.titleThe complex role of prostaglandin E-EP receptor signaling in wound healingen_US
dc.typeArticleen_US
dc.identifier.eissn1522-1490
dc.contributor.departmentDepartment of Nutritional Sciences, University of Arizonaen_US
dc.identifier.journalAmerican journal of physiology. Regulatory, integrative and comparative physiologyen_US
dc.description.note12 month embargo; first published online 9 December 2020en_US
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.en_US
dc.eprint.versionFinal accepted manuscripten_US
dc.source.journaltitleAmerican journal of physiology. Regulatory, integrative and comparative physiology
dc.source.volume320
dc.source.issue3
dc.source.beginpageR287
dc.source.endpageR296
dc.source.countryUnited States


Files in this item

Thumbnail
Name:
PGE2_review_FINAL.pdf
Embargo:
2021-12-09
Size:
447.5Kb
Format:
PDF
Description:
Final Accepted Manuscript

This item appears in the following Collection(s)

Show simple item record