The complex role of prostaglandin E-EP receptor signaling in wound healing
| dc.contributor.author | Gilman, Kristy E | |
| dc.contributor.author | Limesand, Kirsten H | |
| dc.date.accessioned | 2021-04-08T02:06:16Z | |
| dc.date.available | 2021-04-08T02:06:16Z | |
| dc.date.issued | 2020-12-09 | |
| dc.identifier.citation | Gilman, K. E., & Limesand, K. H. (2020). The complex role of Prostaglandin E2-EP receptor signaling in wound healing. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. | en_US |
| dc.identifier.issn | 1522-1490 | |
| dc.identifier.pmid | 33296281 | |
| dc.identifier.doi | 10.1152/ajpregu.00185.2020 | |
| dc.identifier.uri | http://hdl.handle.net/10150/657646 | |
| dc.description.abstract | Prostaglandins are critical lipid mediators involved in the wound healing response, with prostaglandin E2 (PGE2) being the most complex and exhibiting the most diverse physiological outputs. PGE2 signals via four G protein-coupled receptors, termed EP-receptors 1-4 that induce distinct signaling pathways upon activation and lead to an array of different outputs. Recent studies examining the role of PGE2 and EP receptor signaling in wound healing following various forms of tissue damage are discussed in this review. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | American Physiological Society | en_US |
| dc.rights | Copyright © 2021 the American Physiological Society. | en_US |
| dc.rights.uri | http://rightsstatements.org/vocab/InC/1.0/ | en_US |
| dc.subject | cell signaling | en_US |
| dc.subject | Prostaglandins | en_US |
| dc.subject | repair | en_US |
| dc.subject | tissue damage | en_US |
| dc.subject | wound healing | en_US |
| dc.title | The complex role of prostaglandin E-EP receptor signaling in wound healing | en_US |
| dc.type | Article | en_US |
| dc.identifier.eissn | 1522-1490 | |
| dc.contributor.department | Department of Nutritional Sciences, University of Arizona | en_US |
| dc.identifier.journal | American journal of physiology. Regulatory, integrative and comparative physiology | en_US |
| dc.description.note | 12 month embargo; first published online 9 December 2020 | en_US |
| dc.description.collectioninformation | This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu. | en_US |
| dc.eprint.version | Final accepted manuscript | en_US |
| dc.source.journaltitle | American journal of physiology. Regulatory, integrative and comparative physiology | |
| dc.source.volume | 320 | |
| dc.source.issue | 3 | |
| dc.source.beginpage | R287 | |
| dc.source.endpage | R296 | |
| dc.source.country | United States |
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