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    Integrating Touchscreen-Based Geriatric Assessment and Frailty Screening for Adults With Multiple Myeloma to Drive Personalized Treatment Decisions

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    jop.19.00208.pdf
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    Author
    Nathwani, Nitya
    Kurtin, Sandra E
    Lipe, Brea
    Mohile, Supriya Gupta
    Catamero, Donna D
    Wujcik, Debra
    Birchard, Kristy
    Davis, Agnes
    Dudley, William
    Tompkins Stricker, Carrie
    Wildes, Tanya Marya
    Show allShow less
    Affiliation
    Univ Arizona, Ctr Canc
    Issue Date
    2019-11-25
    
    Metadata
    Show full item record
    Publisher
    AMER SOC CLINICAL ONCOLOGY
    Citation
    Nathwani, N., Kurtin, S. E., Lipe, B., Mohile, S. G., Catamero, D. D., Wujcik, D., ... & Wildes, T. M. (2020). Integrating touchscreen-based geriatric assessment and frailty screening for adults with multiple myeloma to drive personalized treatment decisions. JCO oncology practice, 16(1), e92-e99.
    Journal
    JCO ONCOLOGY PRACTICE
    Rights
    © 2019 by American Society of Clinical Oncology.
    Collection Information
    This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.
    Abstract
    Patients were white (72%; n = 86), mean age was 72 years (range, 65-85 years), and averaged 7.71 minutes (range, 2-17 minutes) for survey completion. Providers averaged 3.2 minutes (range, 1-10 minutes) to review mGA results. Using International Myeloma Working Group frailty score, patients were fit (39%; n = 64), intermediate fit (33%; n = 55), or frail (28%; n = 46). Providers selected more aggressive treatments in 16.3% of patients and decreased treatment intensity in 34% of patients; treatment intensification was more common for fit patients and milder treatments for frail patients (χ2 = 20.02; P < .0001). Transplant eligibility significantly correlated with fit status and transplant ineligibility with frail status (P = .004). Outcomes on 144 patients 3 months post study visit showed 19.4% (n = 28) had grade ≥ 3 hematologic toxicities, 38.9% (n = 56) had dose modifications, and 18% (n = 26) had early therapy cessation.
    Note
    12 month embargo; first published online 25 November 2019
    ISSN
    2688-1527
    EISSN
    2688-1535
    PubMed ID
    31765266
    DOI
    10.1200/JOP.19.00208
    Version
    Final published version
    ae974a485f413a2113503eed53cd6c53
    10.1200/JOP.19.00208
    Scopus Count
    Collections
    UA Faculty Publications

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