AuthorGuzman, Lindsay Eileen
AdvisorJewett, John C.
MetadataShow full item record
PublisherThe University of Arizona.
RightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction, presentation (such as public display or performance) of protected items is prohibited except with permission of the author.
AbstractBenzene diazonium (BDz) ions are electrophiles reactive to aromatic amino acids such as tyrosine and histidine. Protected triazabutadienes are chemical probes that generate BDz ions for selective protein labeling. This dissertation summarizes the design and synthesis of protected triazabutadiene molecules. The reactivity of protected triazabutadienes was explored. A functionalized protected triazabutadiene was synthesized. Experiments were performed to determine in vivo reactivity of the protected triazabutadiene in mosquito larvae, Ae. aegypti.
Degree ProgramGraduate College