Think globally, act locally: Centrosome-localized mRNAs ensure mitotic fidelity

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Author
Zarnescu, Daniela C
Affiliation
Molecular and Cellular Biology, University of Arizona
Issue Date
2020-11-20

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Publisher
Rockefeller University Press
Citation
Zarnescu, D. C. (2020). Think globally, act locally: Centrosome-localized mRNAs ensure mitotic fidelity. Journal of Cell Biology, 219(12).
Journal
Journal of cell biology
Rights
© 2020 Zarnescu. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
Collection Information
This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.
Abstract
The functional importance of mRNA localization to centrosomes is unclear. Ryder et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.202004101) identify fragile-X mental retardation protein as a regulator of centrocortin (cen) mRNA dynamics in Drosophila. Mistargeting of cen impairs division and development, indicating that cen mRNA localization to centrosomes ensures mitotic fidelity.
Note
Open access article
ISSN
1540-8140
EISSN
1540-8140
PubMed ID
33216116
DOI
10.1083/jcb.202010172
Version
Final published version
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© 2020 Zarnescu. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
Except where otherwise noted, this item's license is described as © 2020 Zarnescu. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).