We are upgrading the repository! A content freeze is in effect until November 22nd, 2024 - no new submissions will be accepted; however, all content already published will remain publicly available. Please reach out to repository@u.library.arizona.edu with your questions, or if you are a UA affiliate who needs to make content available soon. Note that any new user accounts created after September 22, 2024 will need to be recreated by the user in November after our migration is completed.
Comparison of Short and Long-Term Outcomes of Metabolic and Bariatric Surgery in Adolescents and Adults
Author
Cody Stanford, FatimaMushannen, Tasnim
Cortez, Priscilla
Campoverde Reyes, Karen J
Lee, Hang
Gee, Denise W
Pratt, Janey S
Boepple, Paul A
Bredella, Miriam A
Misra, Madhumita
Singhal, Vibha
Affiliation
Univ Arizona, Coll Sci, Dept BiolIssue Date
2020-03-24
Metadata
Show full item recordPublisher
FRONTIERS MEDIA SACitation
Stanford, F. C., Mushannen, T., Cortez, P., Campoverde Reyes, K. J., Lee, H., Gee, D. W., ... & Singhal, V. (2020). Comparison of short and long-term outcomes of metabolic and bariatric surgery in adolescents and adults. Frontiers in Endocrinology, 11, 157.Journal
FRONTIERS IN ENDOCRINOLOGYRights
Copyright © 2020 Stanford, Mushannen, Cortez, Campoverde Reyes, Lee, Gee, Pratt, Boepple, Bredella, Misra and Singhal. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).Collection Information
This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.Abstract
Objective: We sought to compare the short and long-term outcomes of MBS in adolescents vs. adults who have undergone a Roux-en-Y gastric bypass (RYGB) or Sleeve gastrectomy (SG). Design: Retrospective cohort study. Setting: Single tertiary care academic referral center. Participants: One hundred fifty adolescent (≤ 21-years) and adult (>21-years) subjects with severe obesity between 15 and 70 years of age who underwent RYGB or SG. Outcomes: Metabolic parameters, weight and height measures were obtained pre-and post-surgery (at 3 and 6 months, and then annually for 4 years). Results: Median pre-surgical body mass index (BMI) was higher in adolescents (n = 76) vs. adults (n = 74): 50 (45-57) vs. 44 (40-51) kg/m2 (p < 0.0001). However, obesity related complications were greater in adults vs. adolescents: 66 vs. 21% had hypertension, 68 vs. 28% had dyslipidemia, and 42 vs. 21% had type 2 diabetes mellitus (all p < 0.010). % BMI reduction and % weight loss (WL) were greater in adolescents vs. adults at all time points (p < 0.050). %WL was higher in adolescents who underwent SG at each time point (p < 0.050), and trended higher among adolescents who underwent RYGB (p = 0.060), compared to adults with the respective procedure. Follow-up data showed greater resolution of type 2 diabetes and hypertension in adolescents than adults (87.5 vs. 54.8%; p = 0.04, and 68.7 vs. 35.4%; p = 0.040). Conclusion: Adolescents compared to adults had greater reductions in BMI and weight, even at 4 years, and greater resolution of type 2 diabetes and hypertension. Earlier intervention in the treatment of severe obesity with MBS may lead to better outcomes.Note
Open access journalISSN
1664-2392PubMed ID
32265846Version
Final published versionae974a485f413a2113503eed53cd6c53
10.3389/fendo.2020.00157
Scopus Count
Collections
Except where otherwise noted, this item's license is described as Copyright © 2020 Stanford, Mushannen, Cortez, Campoverde Reyes, Lee, Gee, Pratt, Boepple, Bredella, Misra and Singhal. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Related articles
- Ten-year outcomes after Roux-en-Y gastric bypass and sleeve gastrectomy: an observational nonrandomized cohort study.
- Authors: Jiménez A, Ibarzabal A, Moizé V, Pané A, Andreu A, Molero J, de Hollanda A, Flores L, Ortega E, Lacy A, Vidal J
- Issue date: 2019 Mar
- Weight change and health outcomes at 3 years after bariatric surgery among individuals with severe obesity.
- Authors: Courcoulas AP, Christian NJ, Belle SH, Berk PD, Flum DR, Garcia L, Horlick M, Kalarchian MA, King WC, Mitchell JE, Patterson EJ, Pender JR, Pomp A, Pories WJ, Thirlby RC, Yanovski SZ, Wolfe BM, Longitudinal Assessment of Bariatric Surgery (LABS) Consortium
- Issue date: 2013 Dec 11
- [Comparison of 1-year outcomes between Roux-en-Y gastric bypass and sleeve gastrectomy with Roux-en-Y duodenojejunal bypass in the patients of obesity with type 2 diabetes mellitus].
- Authors: Liang H, Si YM, Lin SB, Shen JJ, Guan W
- Issue date: 2023 Nov 25
- Long-Term Results of Bariatric Surgery in Adolescents with at Least 5 Years of Follow-up: a Systematic Review and Meta-Analysis.
- Authors: Wu Z, Gao Z, Qiao Y, Chen F, Guan B, Wu L, Cheng L, Huang S, Yang J
- Issue date: 2023 Jun
- Long-Term Weight Loss and Metabolic Syndrome Remission after Bariatric Surgery: The Effect of Sex, Age, Metabolic Parameters and Surgical Technique - A 4-Year Follow-Up Study.
- Authors: Guerreiro V, Neves JS, Salazar D, Ferreira MJ, Oliveira SC, Souteiro P, Pedro J, Magalhães D, Varela A, Belo S, Freitas P, Carvalho D, AMTCO Group
- Issue date: 2019