Characteristics and risk factors for early-onset metachronous colorectal adenoma

Abstract

Aim: Compare risk factors for early-onset-metachronous colorectal adenoma (EOMCA) among individuals Materials & methods: Descriptive statistics compared clinical/demographic characteristics for individuals Results: N = A total of 1623 participants. Individuals <50 years (vs >= 50) had higher smoking rates, greater intake of red meat, monounsaturated fatty acids, total fat and less sleep, sedentary behavior, aspirin intake, supplemental calcium use and higher mean energy-adjusted dietary inflammatory index (E-DII) score (pro-inflammatory diet) (all p <= 0.001). Odds of EOMCA were higher among smokers and participants reporting previous polyp(s). Overall odds of EOMCA were lower among individuals <= 50. Conclusion: History of previous polyps and smoking were risk factors for EOMCA. Lifestyle factors require further research.