Use of Palpation Imaging in Diagnosis of Breast Diseases: A Way to Improve the Detection Rate
AffiliationDepartment of Internal Medicine, University of Arizona College of Medicine
MetadataShow full item record
CitationDing, Y., Sun, C., Zhou, Q., Cheng, C., Yan, C., & Wang, B. (2020). Use of Palpation Imaging in Diagnosis of Breast Diseases: A Way to Improve the Detection Rate. Medical Science Monitor: International Medical Journal of Experimental and Clinical Research, 26, e927553-1.
JournalMedical science monitor : international medical journal of experimental and clinical research
RightsCopyright © Medical Science Monitor. This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0).
Collection InformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at email@example.com.
AbstractBACKGROUND Breast diseases pose increasing threat to women health as peoples lifestyle changes. The aim of this study was to investigate the clinical application value of Palpation Imaging (PI) in the diagnosis of breast diseases. MATERIAL AND METHODS From October 2019 to February 2020, 184 patients with 225 breast lesions were examined by using PI, ultrasound, and mammography in the department of Breast Surgery, the First Affiliated Hospital of Anhui Medical University. All cases were confirmed pathologically by core-needle biopsy or excisional biopsy. The cut-off value of the PI tests was determined by receiver operating characteristic (ROC) curve. We compared the examination results of PI with ultrasound and mammography to analyze the diagnostic value of PI. RESULTS Pathological examination revealed that 186/225(82.67%) lesions were benign, while 39 were malignant. All 8 parameters of PI were significantly correlated with pathological findings (P<0.05). The best cut-off value for the PI score was 19.5 and the area under the curve (AUC) for the PI was 0.921 (95% CI: 0.874-0.968, P<0.001) with 89.7% sensitivity and 86.0% specificity. PI showed greater sensitivity (89.7%) and its specificity (86.0% vs. 86.4%, P=0.931) and accuracy (86.7% vs. 84.6%, P=0.604) were similar to those of mammography. The combination of 3 types of test is superior to a single examination. The sensitivity was 100% and the specificity was 98.8%. CONCLUSIONS PI has high clinical value in differentiation of benign and malignant breast lesions. Combination examination has the potential to improve the detection of breast cancer in screening and diagnostic capacities and can be used as a supplement to ultrasound and mammography.
NoteOpen access journal
VersionFinal published version
Except where otherwise noted, this item's license is described as Copyright © Medical Science Monitor. This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0).
- A comparison of mammography and ultrasound in women with breast disease: a receiver operating characteristic analysis.
- Authors: Ying X, Lin Y, Xia X, Hu B, Zhu Z, He P
- Issue date: 2012 Mar-Apr
- Differentiation of benign and malignant breast lesions by mechanical imaging.
- Authors: Egorov V, Kearney T, Pollak SB, Rohatgi C, Sarvazyan N, Airapetian S, Browning S, Sarvazyan A
- Issue date: 2009 Nov
- [Comparative analysis of early diagnostic tools for breast cancer].
- Authors: Shen SJ, Sun Q, Xu YL, Zhou YD, Guan JH, Mao F, Lin Y, Wang XJ, Han SM
- Issue date: 2012 Nov
- Triple approach in the diagnosis of dominant breast masses: combined physical examination, mammography, and fine-needle aspiration.
- Authors: Kaufman Z, Shpitz B, Shapiro M, Rona R, Lew S, Dinbar A
- Issue date: 1994 Aug
- [Electrical impedance scanning in the differentiation of suspicious breast lesions: comparison with mammography, ultrasound and histopathology].
- Authors: Fuchsjäger MH, Helbich TH, Ringl H, Funovics MA, Rudas M, Riedl C, Pfarl G
- Issue date: 2002 Dec