AffiliationDepartment of Internal Medicine, University of Arizona
KeywordsAcute kidney injury
Chronic kidney disease
MetadataShow full item record
CitationPatel, B., Kalan, M. E., Khosravian, M., Tolouian, A., Tolouian, R., Aboufazeli, M., ... & Alirezaei, A. (2020). Lung cancer and kidney injury: an updated review. Journal of Nephropathology, 10(2).
JournalJournal of Nephropathology
RightsCopyright © 2021 The Author(s); Published by Society of Diabetic Nephropathy Prevention. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0).
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AbstractLung cancer is the leading cause of cancer deaths worldwide, accounting for an estimated 1.8 million deaths. Lung cancer is also the most common primary cancer leading to soft tissue (ST) metastasis. Renal disease may occur as a direct or indirect consequence of the cancer itself (e.g., post-renal obstruction, compression, or infiltration), its treatment (e.g., radiotherapy or chemotherapy), or its related complications (e.g., opportunistic infection). Existing evidence shows that the most frequent primary solid tumor responsible for renal metastasis is pulmonary carcinoma, followed by gastric, breast, soft tissue, and thyroid carcinomas. Chronic kidney disease is a potential risk factor in the survival of patients with lung cancer. In this review, we will discuss causes of kidney injury in relation to lung cancer, potential mechanisms of kidney injury, and treatment options. © 2021 The Author(s); Published by Society of Diabetic Nephropathy Prevention.
NoteOpen access journal
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Except where otherwise noted, this item's license is described as Copyright © 2021 The Author(s); Published by Society of Diabetic Nephropathy Prevention. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0).