Cycloartane- And Lanostane-Type Triterpenoids from the Resin of Parthenium argentatum AZ-2, a Byproduct of Guayule Rubber Production
Affiliation
Southwest Center for Natural Products Research, School of Natural Resources and the Environment, College of Agriculture and Life Sciences, University of ArizonaIssue Date
2021Metadata
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American Chemical SocietyCitation
Xu, Y.-M., Madasu, C., Liu, M. X., Wijeratne, E. M. K., Dierig, D., White, B., Molnár, I., & Gunatilaka, A. A. L. (2021). Cycloartane- And Lanostane-Type Triterpenoids from the Resin of Parthenium argentatum AZ-2, a Byproduct of Guayule Rubber Production. ACS Omega.Journal
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Copyright © 2021 The Authors. Published by American Chemical Society. This work is licensed under a Creative Commons Attribution Noncommercial No Derivatives 4.0 International License.Collection Information
This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.Abstract
A total of 12 new cycloartane- and lanostane-type triterpenoids including 16-deoxyargentatin A (1), 16-deoxyisoargentatin A (2), 7-oxoisoargentatin A (3), 24-epi-argentatin H (4), 24-O-p-anisoylargentatin C (5), 24-O-trans-cinnamoylargentatin C (6), 16-dehydroargentatin C (7), 16,17(20)-didehydroargentatin C (8), isoargentatin C (9), isoargentatin H (10), 3-epi-quisquagenin (11), and isoquisquagenin (12) together with 10 known triterpenoids (13-22) were isolated from the resin of Parthenium argentatum AZ-2 obtained as a byproduct of Bridgestone guayule rubber production. The structures of new triterpenoids 1-12 and argentatin H (13), which has previously been characterized as its diacetate (23), were elucidated by extensive analysis of their spectroscopic data and chemical conversions, and the known compounds 14-22 were identified by comparison of their spectroscopic data with those reported. Of these, 13, 14, and 18 exhibited weak cytotoxic activity for several cancer cell lines. © 2021 American Chemical Society. All rights reserved.Note
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Except where otherwise noted, this item's license is described as Copyright © 2021 The Authors. Published by American Chemical Society. This work is licensed under a Creative Commons Attribution Noncommercial No Derivatives 4.0 International License.