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dc.contributor.authorTrejo, Mario Jesus
dc.contributor.authorSoliman, Amr S
dc.contributor.authorChen, Yuli
dc.contributor.authorKalima, Mulele
dc.contributor.authorChuba, Alick
dc.contributor.authorChama, Eslone
dc.contributor.authorMwaba, Catherine K
dc.contributor.authorBanda, Lewis
dc.contributor.authorLishimpi, Kennedy
dc.date.accessioned2021-08-04T20:56:22Z
dc.date.available2021-08-04T20:56:22Z
dc.date.issued2021-06-14
dc.identifier.citationTrejo, M. J., Soliman, A. S., Chen, Y., Kalima, M., Chuba, A., Chama, E., Mwaba, C. K., Banda, L., & Lishimpi, K. (2021). Effects of HIV infection on metastatic cervical cancer and age at diagnosis among patients in Lusaka, Zambia. International Journal of Gynecology and Obstetrics.en_US
dc.identifier.pmid34121186
dc.identifier.doi10.1002/ijgo.13784
dc.identifier.urihttp://hdl.handle.net/10150/661109
dc.description.abstractObjective: To examine the association between the duration of HIV infection and the stage of cervical cancer in Lusaka, Zambia. Methods: This retrospective case-case study included 1583 cervical cancer patients from the Cancer Diseases Hospital in Lusaka, Zambia. A sub-population of HIV-positive patients with additional clinical HIV information was identified following linkage of cancer and HIV databases. Logistic regression models examined the relationship between HIV status and early-onset cervical cancer diagnosis, and between HIV infection duration and initial diagnosis of metastatic cervical cancer. Results: The study population had an average age of 49 years and 40.9% had an initial diagnosis of metastatic cancer. HIV-positive women were more than twice as likely to be diagnosed at early-onset cervical cancer compared with HIV-negative women. Among the sub-population of HIV-positive patients, a longer duration of HIV infection was associated with 20% lowered odds of initial metastatic cancer diagnosis. Conclusion: The availability, accessibility, and impact of the cervical screening program in this population should be further examined to elucidate the relationship between cervical screening, age, and duration of HIV infection and the the stage of diagnosis of cervical cancer. © 2021 International Federation of Gynecology and Obstetrics.en_US
dc.language.isoenen_US
dc.publisherJohn Wiley and Sons Ltden_US
dc.rights© 2021 International Federation of Gynecology and Obstetrics.en_US
dc.rights.urihttp://rightsstatements.org/vocab/InC/1.0/en_US
dc.subjectHIVen_US
dc.subjectZambiaen_US
dc.subjectAgeen_US
dc.subjectCervical Canceren_US
dc.subjectstageen_US
dc.titleEffects of HIV infection on metastatic cervical cancer and age at diagnosis among patients in Lusaka, Zambiaen_US
dc.typeArticleen_US
dc.identifier.eissn1879-3479
dc.contributor.departmentDepartment of Epidemiology and Biostatistics, Mel & Enid Zuckerman College of Public Health, The University of Arizonaen_US
dc.identifier.journalInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetricsen_US
dc.description.note12 month embargo; first published: 14 June 2021en_US
dc.description.collectioninformationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at repository@u.library.arizona.edu.en_US
dc.eprint.versionFinal accepted manuscripten_US
dc.source.journaltitleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
dc.source.countryUnited States
dc.source.countryUnited States
dc.source.countryUnited States


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