Implication of IL-6 Neuroinflammation in the Context of Insomnia as a Risk Factor for Neurodegeneration
Publisher
The University of Arizona.Rights
Copyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction, presentation (such as public display or performance) of protected items is prohibited except with permission of the author.Abstract
Sleep is a complex and required physiological process that is important for the health and function of a person. Disturbances in sleep have been linked to neurodegenerative diseases, yet it is unknown through what mechanism insomnia may be playing a role in this pathology. Recently, there has been emphasis in the field implicating disrupted metabolite clearance during slow wave sleep (SWS) in neurodegenerative diseases. However, the context of inflammation, specifically the pro-inflammatory cytokine IL-6, a known mediator of sleepiness, may provide important insight into sleep’s role in neurodegenerative diseases.Type
textElectronic Thesis
Degree Name
M.S.Degree Level
mastersDegree Program
Graduate CollegeCellular & Molecular Medicine